Results 31 to 40 of about 29,605 (176)

Trouble in the Tank: A Case Report of Fatal Scuticociliate Encephalitis in a Whitetip Reef Shark (Triaenodon obesus)

open access: yes
Journal of Fish Diseases, EarlyView.
Hella Schwegler   +5 more
wiley   +1 more source

Magnetic Resonance Imaging Features of Spontaneous Subdural Hematoma Secondary to Necrotizing Encephalitis in a Dog

open access: yesVeterinary Radiology &Ultrasound, Volume 66, Issue 6, November 2025.
ABSTRACT A 4‐year‐old castrated male Pomeranian dog with a 2‐year history of necrotizing encephalitis (NE) presented for acute neurological deterioration without trauma. Magnetic resonance imaging (MRI) revealed a broad crescent‐shaped lesion with mixed signal intensities on T1‐ and T2‐weighted images, hypointense areas on T2* images, contrast ...
Eunjee Kim   +4 more
wiley   +1 more source

Safety, tolerability, immunogenicity, and efficacy of ABvac40 active immunotherapy against Aβ40 in patients with mild cognitive impairment or very mild Alzheimer's disease: A randomized, double‐blind, placebo‐controlled phase 2 study

open access: yesAlzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION ABvac40 is an investigational active immunotherapy (vaccine) targeting Aβ40. This study assessed the safety and immunogenicity of ABvac40 in patients with amnestic mild cognitive impairment or very mild Alzheimer's disease. METHODS AB1601 was a multicenter, randomized, double‐blind, placebo‐controlled phase 2 study.
María Pascual‐Lucas   +15 more
wiley   +1 more source

Autoantibodies against TRIM46 identified in a dog suffering from suspected meningoencephalomyelitis of unknown origin

open access: yes
Journal of Small Animal Practice, EarlyView.
P. L. Heidemann   +6 more
wiley   +1 more source

Bloomy Rind Sign in Leptomeningeal Metastasis of Primary Lung Adenocarcinoma

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT The bloomy rind sign, which appears as hyperintensities on FLAIR along the surface of the brainstem without gadolinium contrast enhancement, is a rare and early finding indicative of leptomeningeal metastasis in patients with lung adenocarcinoma, often associated with EGFR gene mutations.
Wenyuan Tao   +3 more
wiley   +1 more source

Neuronal surface and intracellular antibody testing in patients with long‐term epilepsy

open access: yesEpilepsia Open, Volume 10, Issue 5, Page 1373-1387, October 2025.
Abstract Objective We aimed to investigate the frequency of neuronal surface and intracellular antibodies in individuals with long‐term epilepsy and the associated clinical and laboratory characteristics. Methods We tested sera from 223 patients with epilepsy without signs of autoimmune encephalitis and 12 patients with epilepsy and a subacute onset of
Nancy Watanabe   +9 more
wiley   +1 more source

An In Vitro Calibration Model for Vancomycin Quantification in Brain Extracellular Fluid: Toward Improved Dosing in Postoperative Infections

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
Overview of the study design, methodology, and main findings on vancomycin relative recovery using in vitro microdialysis under neurocritical care–simulated conditions. ABSTRACT Postoperative central nervous system (CNS) infections are associated with high mortality and present a therapeutic challenge due to limited antibiotic penetration into the ...
Skaistė Žukaitienė   +6 more
wiley   +1 more source

Diagnostic Yield of Anti‐Neuronal Antibody Testing in Patients Suspected of an Infectious Encephalitis

open access: yesEuropean Journal of Neurology, Volume 32, Issue 10, October 2025.
In a retrospective analysis of suspected autoimmune encephalitis (AIE) cases from a prospective cohort including patients with an acute presentation, nine cases of antibody‐positive AIE were identified during hospitalization. Extensive additional anti‐neuronal antibody testing did not yield additional cases of antibody‐positive AIE. ABSTRACT Background
Liora ter Horst   +15 more
wiley   +1 more source

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