Results 31 to 40 of about 66,177 (302)

Delineating neuroinflammation, parasite CNS invasion, and blood-brain barrier dysfunction in an experimental murine model of human African trypanosomiasis [PDF]

, 2017
Although Trypanosoma brucei spp. was first detected by Aldo Castellani in CSF samples taken from sleeping sickness patients over a century ago there is still a great deal of debate surrounding the timing, route and effects of transmigration of the ...
Bradley, Barbara, Kennedy, Peter G.E., Rodgers, Jean   +2 more
core   +1 more source

Chemokine receptor CXCR3 is required for lethal brain pathology but not pathogen clearance during cryptococcal meningoencephalitis

Science Advances, 2020
CXCR3 axis promotes lethal CNS pathology but is a dispensable fungal control in cryptococcal meningoencephalitis. Cryptococcal meningoencephalitis (CM) is the major cause of infection-related neurological death, typically seen in immunocompromised ...
Jintao Xu, L. Neal, Anutosh Ganguly, Jessica L. Kolbe, Jessica C. Hargarten, Waleed Elsegeiny, Christopher Hollingsworth, Xiumiao He, Mike Ivey, Rafael Lopez, Jessica Zhao, B. Segal, P. Williamson, M. Olszewski   +13 more
semanticscholar   +1 more source

False negative diagnostic errors with polymerase chain reaction for the detection of cryptococcal meningoencephalitis.

Medical Mycology, 2020
The accuracy of the BioFire FilmArray Meningitis/Encephalitis (ME) panel for the identification of Cryptococcus has recently been called into question.
P. Lewis, Cameron Lanier, Paras D. Patel, Whitney D Krolikowski, Matthew A Krolikowski   +4 more
semanticscholar   +1 more source

Off-Label Use of Crisdesalazine (GedaCure) in Meningoencephalitis in Two Dogs

Veterinary Sciences, 2023
An 8-year-old, castrated male Shih-tzu dog (Case 1) showing ataxia and gait disorder was referred for neurological examination and magnetic resonance imaging.
Saeyoung Lee, Woo-Jin Song, Jongjin Park, Minkun Kim, Sangkyung Choen, Myung-Chul Kim, Hyohoon Jeong, Youngmin Yun   +7 more
doaj   +1 more source

Limited Activity Of Miltefosine In Murine Models Of Cryptococcal Meningoencephalitis And Disseminated Cryptococcosis [PDF]

, 2013
Miltefosine is an alkyl phosphocholine with good oral bioavailability and in vitro activity against Cryptococcus species that has gained interest as an additional agent for cryptococcal infections.
Bocanegra, Rosie, Kirkpatrick, William R., Najvar, Laura K., Patterson, Thomas F., Sorrell, Tania C., Wiederhold, Nathan P.   +5 more
core   +1 more source

Meningoencephalitis associated with COVID-19: a systematic review

Journal of Neurovirology, 2020
With the growing number of COVID-19 cases in recent times. significant set of patients with extra pulmonary symptoms has been reported worldwide. Here we venture out to summarize the clinical profile, investigations, and radiological findings among ...
Ritwick Mondal, Upasana Ganguly, Shramana Deb, Gourav Shome, Subhasish Pramanik, D. Bandyopadhyay, D. Lahiri   +6 more
semanticscholar   +1 more source

Human Chronic Necrotizing Granulomatous Meningoencephalitis: A Novel Case Report

Case Reports in Neurology, 2018
Necrotizing and granulomatous meningoencephalitis are common central nervous system diseases known to affect canines. To date, necrotizing granulomatous meningoencephalitis has yet to be described in humans.
Alexus P. Taddonio, Eric J. Veloso, Kelly J. Baldwin   +2 more
doaj   +1 more source

Relapsing optic neuritis and meningoencephalitis in a child: case report of delayed diagnosis of MOG-IgG syndrome

BMC Neurology, 2019
Background Recurrent optic neuritis (ON) was previously thought to be associated with multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD).
Xiaonan Zhong, Yanyu Chang, Sha Tan, Jingqi Wang, Xiaobo Sun, Aimin Wu, Lisheng Peng, Alexander Y. Lau, Allan G. Kermode, Wei Qiu   +9 more
doaj   +1 more source

Naphthyridine Derivatives Induce Programmed Cell Death in Naegleria fowleri

Pharmaceuticals, 2021
Primary amoebic encephalitis (PAM) caused by the opportunistic pathogen Naegleria fowleri is characterized as a rapid and lethal infection of the brain which ends in the death of the patient in more than 90% of the reported cases.
Aitor Rizo-Liendo, Iñigo Arberas-Jiménez, Endika Martin-Encinas, Ines Sifaoui, María Reyes-Batlle, Javier Chao-Pellicer, Concepción Alonso, Francisco Palacios, José E. Piñero, Jacob Lorenzo-Morales   +9 more
doaj   +1 more source

Human case of West Nile neuroinvasive disease in Portugal, summer 2015 [PDF]

, 2015
A case of West Nile virus (WNV) infection was reported in the Algarve region, Portugal, in the first week of September 2015. WNV is known to circulate in Portugal, with occasional reports in horses and birds (2004 to 2011) and very sporadically human ...
Alves, M. J., Fevereiro, M., Gomes, S., Luz, T., Osório, H. C., Parreira, P., Proença, P., Zé-Zé, L.   +7 more
core   +1 more source