Results 61 to 70 of about 27,449 (171)

New Perspective: Bench to Bedside Evidence of the Role of CD8+ T Cells in Alzheimer's Disease

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
Emerging evidence highlights a previously underappreciated role of CD8+ T cells in Alzheimer's disease (AD). Beyond amyloid‐β and tau pathology, CD8+ T‐cell subsets infiltrate the central nervous system and exhibit functional heterogeneity. Cytotoxic effector CD8+ T cells may exacerbate neuroinflammation and neuronal injury, whereas regulatory or ...
Yong Peng, Shun‐yu Yao, Si‐Liang Wu, Huan Yang, Xiuli Zhang, Sugimoto Kazuo, Jia Liu, Miao‐qiao Du, Lan‐xin Lin, Xu‐hui Kang, Dai‐yi Jiang   +10 more
wiley   +1 more source

Meningoencefalite por Herpesvirus bovino 5 em Minas Gerais: relato de caso clínico Meningoencephalitis by Bovine herpesvirus 5 in Minas Gerais state: clinical case report

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2009
Relata-se um caso de meningoencefalite causada por Herpesvirus bovino 5 (BoHV-5) heritabilityem uma vaca com cinco anos de idade. O animal manifestou quadro clínico inicial de síndrome medular baixa, caracterizada por incoordenação dos membros pélvicos ...
H.M. Aquino Neto, A.U. Carvalho, E.J. Facury Filho, P.M. Ferreira, E.F. Barbosa-Stancioli, Z.I.P. Lobato, M.R. Alvarenga, A.L. Serrano, R.A. Martins, D.A.F. Afonso   +9 more
doaj   +1 more source

Expression of Purinergic and Endothelial Activation Markers in Brain Tissue From Fatal Microcephaly Associated With ZIKV

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background Zika virus (ZIKV) is a flavivirus that has gained global attention due to its association with congenital microcephaly and neuroinflammatory responses. Markers of endothelial activation and purinergic signaling have been identified in the context of ZIKV neuropathogenesis, although the underlying mechanisms remain poorly understood.
Jorge Rodrigues de Sousa, Gustavo Batista Ferro, Leticia Vieira Teixeira, Carlos Silva, Ligia Lima, Orlando Neto, Raimunda Azevedo, Jannifer Oliveira Chiang, Livia Medeiros Neves Casseb, Arnaldo Jorge Martins Filho, Lívia Caricio Martins, Juarez Antônio Simões Quaresma, Pedro Fernando da Costa Vasconcelos   +12 more
wiley   +1 more source

Retrospective analysis of multiplex polymerase chain reaction-based molecular diagnostics (SES) in 70 patients with suspected central nervous system infections: A single-center study

Annals of Indian Academy of Neurology, 2016
Background: Central nervous system (CNS) infections present a grave health care challenge due to high morbidity and mortality. Clinical findings and conventional laboratory assessments are not sufficiently distinct for specific etiologic diagnosis ...
Rama Krishnan Tiruppur Chinnappan Ramalingam, Dipanjan Chakraborty   +1 more
doaj   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

MedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng, Honghao Song, Tianying Li, Yuqing Ma, Chen Yan, Yuhan Cao, Kaiqiang Sun, Chaofeng Han, Hongbin Yuan   +8 more
wiley   +1 more source

Case Report: MOGAD - a steroid-responsive autoimmune meningoencephalitis mimicking infection

Frontiers in Immunology
This case series reports three patients initially managed for presumed infectious meningoencephalitis, who were ultimately diagnosed with myelin oligodendrocyte glycoprotein associated disease (MOGAD). Their clinical presentations were strikingly similar
Yihui Goh, Priscillia Pei Shi Lye, Paul Anantharajah Tambyah, Paul Anantharajah Tambyah, Paul Anantharajah Tambyah, Derek Tuck Loong Soon, Derek Tuck Loong Soon, Nares Smitasin, Nares Smitasin, Jonathan Jia Yuan Ong, Jonathan Jia Yuan Ong, Clement Hsiang Rong Yong, Clement Hsiang Rong Yong, Yee Cheun Chan, Yee Cheun Chan, David Tang, Kay Wei Ping Ng, Kay Wei Ping Ng, Raymond Chee Seong Seet, Raymond Chee Seong Seet, Amy May Lin Quek, Amy May Lin Quek   +21 more
doaj   +1 more source

Langat Virus Biology and Infection

Reviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Flaviviruses pose a major threat to global health and can cause severe disease in animals and humans. Among them, tick‐borne encephalitis virus (TBEV) and related members of the tick‐borne encephalitis (TBE) serocomplex are transmitted primarily by ticks and can lead to neurological disease, including encephalitis and death. Despite many years
Zinaida Klestova, Daniel Sauter, Michael Schindler, Thomas Iftner   +3 more
wiley   +1 more source

Clinical case report on treatment of Listeria monocytogenes meningoencephalitis: Intrathecal injection

Clinical Case Reports, 2018
Key Clinical Message This article mainly reports the process of clinical diagnosis and treatment of a misdiagnosed Listeria monocytogenes meningoencephalitis. The patient's condition is aggravated because of the ineffective prophase therapy. In the later
Xu‐Biao Pan, Zhi‐Xin Wang, Ming‐He Ma, Hong‐Bin Wang, Gui‐Fen Gan, Hai‐Ning Fan   +5 more
doaj   +1 more source

Primary amoebic meningoencephalitis [PDF]

The Laryngoscope, 1978
AbstractAs a serendipitous by‐product of polio virus research, a highly fatal amoebic meningoencephalitis was recognized in animals. The causative microorganisms, contaminants of the viral cultures, were identified as small soil amoebae. These organisms, previously considered non‐pathogenic, are prevalent throughout the world.
openaire   +2 more sources

Primary Meningeal Extraskeletal Osteosarcoma in a Domestic Shorthaired Cat: Case Report and Review of Comparative Pathology

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
A domestic shorthaired cat with neurological signs compatible with a forebrain lesion was investigated with magnetic resonance imaging, revealing a mass with intracranial and extracranial components. Due to the poor prognosis the cat was euthanized, and gross and histopathological examination identified an extraskeletal osteosarcoma with its origin in ...
Jacqueline Poldy, Dario Costanza, Aran Nagendran, Albert Aguilera‐Padros, Tiziana Liuti, Jorge Del‐Pozo   +5 more
wiley   +1 more source