Results 61 to 70 of about 91,813 (297)

Lifetime estrogen exposure and domain-specific cognitive performance: results from the IGNITE study

Frontiers in Aging Neuroscience
IntroductionDisruptions in estrogen exposure (i.e., surgically induced menopause) have been linked to poorer cognitive aging and dementia risk. Hormone therapy use (e.g., birth control, menopausal hormone therapy) has shown mixed associations with ...
Amber Watts, Amber Watts, Shannon Donofry, Shannon Donofry, Hayley Ripperger, Nicole M. Eklund, Lu Wan, Chaeryon Kang, George Grove, Lauren E. Oberlin, Lauren E. Oberlin, Swathi Gujral, Eric D. Vidoni, Jeffrey M. Burns, Edward McAuley, Edward McAuley, Charles H. Hillman, Arthur F. Kramer, Arthur F. Kramer, M. Ilyas Kamboh, Kirk I. Erickson, Kirk I. Erickson   +21 more
doaj   +1 more source

Alternatives of menopausal hormone therapy

Medicinski pregled, 2016
Introduction. It has been generally accepted that the benefits of menopausal hormone therapy outweigh the risks, but there are still some concerns about the administration of menopausal hormone therapy, which has introduced alternative treatments. Pharmacological Alternatives.
Ranko M, Kutlesic, Jasmina, Popovic, Milan, Stefanovic, Predrag, Vukomanovic, Bojan, Lukic, Goran, Lilic   +5 more
openaire   +3 more sources

Estrogen, angiogenesis, immunity and cell metabolism: Solving the puzzle [PDF]

, 2018
Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types including immune and vascular cells. Sex steroid hormones are implicated in cardiovascular protection,
Bolego, Chiara, BOSCARO, CARLOTTA, Cignarella, Andrea, Tedesco, Serena, Trenti, Annalisa, Trevisi, Lucia   +5 more
core   +2 more sources

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

25-Hydroxy vitamin-D, obesity, and associated variables as predictors of breast cancer risk and tamoxifen benefit in NSABP-P1. [PDF]

, 2012
Observational studies suggest that host factors are associated with breast cancer risk. The influence of obesity, vitamin-D status, insulin resistance, inflammation, and elevated adipocytokines in women at high risk of breast cancer is unknown. The NSABP-
Amir, Eitan, Beddows, Samantha, Cecchini, Reena S, Costantino, Joseph P, Ganz, Patricia A, Goodwin, Pamela J, Hood, Nicola   +6 more
core   +1 more source

Gender Disparities in the Prevalence, Trends, and Determinants of Later‐Life Urinary Incontinence: A Disproportionate Burden on Women

AGING MEDICINE, EarlyView.
This study shows that UI prevalence rose steadily in both the USA and UK during the 2010s, driven by aging, comorbidities, and educational changes, with women accounting for 65% of the projected increase in UI cases by 2030. These findings underscore the need for gender‐responsive UI prevention and care strategies, including targeted interventions for ...
Xiyin Chen, Shaoxiang Jiang, Muqi Guo, Hao Zhang, Mouwang Zhou, Yao Yao   +5 more
wiley   +1 more source

Menopausal hormone therapy is associated with having high blood pressure in postmenopausal women: observational cohort study.

PLoS ONE, 2012
BackgroundThe relationship between menopausal hormone therapy (MHT) and cardiovascular risk remains controversial, with a number of studies advocating the use of MHT in reducing risk of cardiovascular diseases, while others have shown it to increase risk.
Christine L Chiu, Sanja Lujic, Charlene Thornton, Aiden O'Loughlin, Angela Makris, Annemarie Hennessy, Joanne M Lind   +6 more
doaj   +1 more source

Development of di(2‐ethylhexyl) phthalate‐containing thioglycolic acid immobilized chitosan mucoadhesive gel as an alternative hormone therapy for menopausal syndrome

Bioengineering & Translational Medicine, 2022
Menopausal syndrome includes the symptoms that most women experience owing to hormone changes after menopause. Although hormone replacement therapy is a common treatment for menopausal syndrome, there are still many side effects and challenges hindering ...
I‐Hsuan Yang, I‐En Lin, Ya‐Jyun Liang, Jhih‐Ni Lin, Tzu‐Chien Chen, Zhi‐Yu Chen, Che‐Yung Kuan, Chih‐Ying Chi, Chi‐Han Li, Hung‐Ming Wu, Feng‐Huei Lin   +10 more
doaj   +1 more source

Menopause, micronutrients, and hormone therapy [PDF]

The American Journal of Clinical Nutrition, 2005
Micronutrient and herbal/phytochemical supplements are of increasing interest as potential alternatives to using estrogen therapy in treating menopausal symptoms. This article provides an overview of the questionnaires that assess menopausal symptoms and research efforts to better standardize symptom assessment.
openaire   +2 more sources