Results 171 to 180 of about 181,989 (257)

Differential FGFR1 copy number status displays unique tumour immune microenvironment in triple‐negative breast cancer

The Journal of Pathology, EarlyView.
Abstract Fibroblast growth factor receptor 1 (FGFR1) amplification, a significant cancer alteration with both prognostic and therapeutic relevance, lacks a standardized definition. The relationship between FGFR1 copy number (CN) variations and tumour microenvironment (TME) characteristics also remains poorly understood.
Yike Gao, Fei Yao, Junyi Pang, Tianlin Sun, Changbin Zhu, Shafei Wu, Zhiyong Liang   +6 more
wiley   +1 more source

Non-Hormonal Treatments for Vasomotor Symptoms of Menopause: An Up-to-Date Review. [PDF]

Cureus
Farhan AS, Farhan HS, Dinfash MT.
europepmc   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Prospective study of reproductive span and menopausal hormone therapy and cognitive decline over 8 years in the Nurses' Health Study. [PDF]

Menopause
Juramt N, Kang JH, Wang DD, Vyas CM, Peng C, Curhan S, Warner ET, Zeleznik OA, Rosner BA, Wang M, Stampfer MJ, Grodstein F, Okereke OI, Eliassen AH.   +13 more
europepmc   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

Understanding the interplay between cognitive changes at menopause, the workplace, and mental health: qualitative findings from the MARIE-UK (WP2a) project. [PDF]

Front Glob Womens Health
Hinchliff S, Potočnik K, Delanerolle G, Taylor J, Elliot K, Fontana D, Saraswat L, Panay N, Talaulikar V, Atkinson C, Kemp HF, Kurmi O, Rathnayake N, Al-Kharusi L, Pathiraja V, Al-Riyami N, Palanisamy R, Eleje GU, Phiri P.   +18 more
europepmc   +1 more source

Towards Responsible Mining in Africa: Problematising the Environmental and Public Health Concerns of Artisanal and Small‐Scale Gold Mining in Ghana

Sustainable Development, EarlyView.
ABSTRACT There have been emerging media reports on the impact of cyanide and mercury use in artisanal and small‐scale gold mining (ASGM) operations on community health, especially among pregnant and non‐pregnant women, ASGM miners, and children in rural Africa.
Francis Arthur‐Holmes, Emmanuel Selasi Tomude, Steve Ahenkora Amoako   +2 more
wiley   +1 more source

Xerostomia in the menopausal transition: are we measuring menopause or its comorbidities? [PDF]

Clinics (Sao Paulo)
Florezi GP, Vanelli L, de Moraes FP, Sorpreso ICE, Soares-Junior JM, Lourenço SV.   +5 more
europepmc   +1 more source

Prevalence and Blood Biochemical Parameters Associated with Sarcopenia Among Korean Postmenopausal Women Aged 50 Years and Older: A Nationwide Cross-Sectional Study. [PDF]

Healthcare (Basel)
Kim S.
europepmc   +1 more source