Results 121 to 130 of about 41,913 (245)

Dysregulation of Oral Microbial Eicosapentaenoic Acid Induced by Chronic Restraint Stress Exacerbates Periodontitis via M1 Macrophage Polarization

Advanced Science, EarlyView.
ABSTRACT The intricate interplay between chronic psychological stress and periodontitis, mediated by oral microbiota and macrophage polarization, remains largely enigmatic. Here, we demonstrate that chronic restraint stress (CRS) exacerbates periodontitis by inducing oral microbial dysbiosis and a consequential shift in host metabolism.
Shihong Luo, Fangzhi Lou, Peiran Yang, Yu Zhang, Li Yan, Yunmei Dong, Bing Yang, Haiyang Wang, Yiyun Liu, Juncai Pu, Richard D. Cannon, Peng Xie, Ping Ji, Xin Jin   +13 more
wiley   +1 more source

Overindebted, unsupported and lonely, and mentally stressed and depressed-exploring the relationship between overindebtedness, social disconnectedness and poor mental health in a population-based Swiss study. [PDF]

BMC Public Health
Hämmig O.
europepmc   +1 more source

Post‐Translational Modifications in Animal Circadian Clocks

Advanced Science, EarlyView.
Circadian clocks coordinate physiology with daily environmental cycles through conserved transcriptional–translational feedback loops. This review summarizes how post‐translational modifications fine‐tune clock function, highlights the evolutionary convergence of circadian timekeeping in Drosophila and mammals, and emphasizes the central of these ...
Xianhui Liu, Yong Zhang
wiley   +1 more source

Comment on "the impact of sleep duration on the incidence of new-onset chronic kidney disease in community-dwelling adults: a nationwide cohort study". [PDF]

Ann Med
Xu D.
europepmc   +1 more source

Rapid and Direct Detection of Methamphetamine in Biofluids using a MXene‐Enabled Electrochemical Sensor

Advanced Science, EarlyView.
A MXene‐enhanced electrochemical sensor enables the rapid and direct detection of methamphetamine. Molecular simulations reveal that specific MXene surface functional groups act as key signal amplifiers by facilitating interfacial interactions. The sensor demonstrates high sensitivity and robust performance in complex biological matrices.
Ri Wang, Xiaofei Deng, Bo Chen, Jienan Shen, Wei Xu, Yingjie Zhu, Yi Zhang, Hui Yang   +7 more
wiley   +1 more source

Pre-hospital cardiac arrest: a call for moral agency in modern medical practice. [PDF]

BMC Med Ethics
Joerck CL, Kristensen ASS, Lunding MH, Binderup LG, Huniche L, Smith MA, Mikkelsen S, Bruun H.   +7 more
europepmc   +1 more source

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

Advanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv, Yu Cao, Yuhan Wang, Yunhao Wu, Yingying Zhang, Kuanghao Ye, Xian Qiu, Qingfang Sun, Liuguan Bian, Halimureti Paerhati, Valerie Voon, Shikun Zhan, Bomin Sun   +12 more
wiley   +1 more source

"Just lose weight": weight-based medical bias and experiential expertise in intracranial hypertension. [PDF]

Front Psychiatry
Moes K.
europepmc   +1 more source

The Internal‐External Synergy of Self‐Reconstructed C/NiFeOOH/SeO42− for Efficient and Stable Seawater Electrolysis

Advanced Science, EarlyView.
This work presents an internal‐external synergy strategy where a C@FeNi2Se4 core‐shell precursor reconstructes in to a C/FeNi2Se4/SeO42− architecture during OER. The inner C stabilizes active sites while the outer SeO42− layer repels Cl−, achieving efficient and stable seawater oxidation for over 150 h at 400 mA cm−2.
Zhe Sun, Yitong Yin, Siyuan Liu, Bo Liao, Bing He, Zhaojie Wang, Xiaoqing Lu, Xingheng Zhang   +7 more
wiley   +1 more source

Hearing impairment and cognitive decline: Alternative explanations to causality. [PDF]

J Alzheimers Dis
Merten N, Dawes P, Munro KJ, Brenowitz WD.   +3 more
europepmc   +1 more source