Results 121 to 130 of about 1,814,103 (261)

Engagement in binge eating and fasting associated with poorer sleep quality in an online sample of adults

open access: yesJournal of Eating Disorders
Objectives Both disordered eating and disturbed sleep represent significant threats to mental health. Accumulating evidence suggests that disordered eating behaviors and sleep problems co-occur.
Leah A. Irish   +3 more
doaj   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

open access: yesAdvanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang   +11 more
wiley   +1 more source

D2P2: database of disordered protein predictions [PDF]

open access: yes, 2013
We present the Database of Disordered Protein Prediction (D2P2), available at http://d2p2.pro (including website source code). A battery of disorder predictors and their variants, VL-XT, VSL2b, PrDOS, PV2, Espritz and IUPred, were run on all protein ...
Oates, Matt E.   +3 more
core   +1 more source

Child and Adolescent Mental Health In-patient Unit, Merlin Park University Hospital, Approved Centre Inspection Report 27-29 October 2015

open access: yes, 2016
Section 51 (1) (a) of the Mental Health Act (2001). States that the principal function of the Inspector shall be to “visit and inspect every approved centre at least once a year in which the commencement of this section falls and to visit and inspect any
Mental Health Commission (MHC)
core  

The Mind From Within: Visceral Roots of Human Cognition

open access: yesAdvanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti   +1 more
wiley   +1 more source

The interplay between social media use, poor sleep, and disordered eating: a narrative review

open access: yesCogent Mental Health
Emerging evidence suggests a complex, potentially reciprocal relationship between social media use, poor sleep, and disordered eating, each associated with negative mental and physical health outcomes.
Silvia Cerolini   +2 more
doaj   +1 more source

Centre for Mental Health Care & Recovery, Bantry General Hospital, Approved Centre Inspection Report 22-23 October 2015

open access: yes, 2015
Section 51 (1) (a) of the Mental Health Act (2001). States that the principal function of the Inspector shall be to “visit and inspect every approved centre at least once a year in which the commencement of this section falls and to visit and inspect any
Mental Health Commission (MHC)
core  

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

open access: yesAdvanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj   +25 more
wiley   +1 more source

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