Results 191 to 200 of about 1,050,766 (318)

Combinations of mental disorders and their association with mortality in the UK Biobank. [PDF]

BMC Psychiatry
Boschesi Barros V, Chiavegatto Filho ADP.   +1 more
europepmc   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Mental Disorders and Quality of Life in Patients With Pulmonary Arterial Hypertension Treated With Sotatercept. [PDF]

Pulm Circ
Fuge J, Olsson KM, Remmert K, Stapel B, Kamp JC, Park DH, Hoeper MM, Winter L, Kahl KG.   +8 more
europepmc   +1 more source

Mental health disorders [PDF]

British Dental Journal, 2020
openaire   +2 more sources

Adrenalectomy in Mental Disorder [PDF]

BMJ, 1947
E C, DAX, E J R, SMITH, F, REITMAN
openaire   +2 more sources

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source

Protocol: Effectiveness of Artificial Intelligence-Based Psychotherapy in Treating Mental Disorders. [PDF]

Campbell Syst Rev
Soni AK, Singh VK, Kumar M.
europepmc   +1 more source

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Interventions for common mental disorders tested in Cochrane reviews: an analysis of quality of evidence and efficacy. [PDF]

World Psychiatry
Leichsenring F, Flückiger C, Heim N, Hoyer J, Koletsi D, Leweke F, Luyten P, Munder T, Sell C, Spitzer C, Steinert C, Ioannidis JPA.   +11 more
europepmc   +1 more source

Mood Disorder Begins in the Mouth: Periodontitis Mediates Anxiety‐Like Behaviors

Advanced Science, EarlyView.
ABSTRACT The previous study elucidated that the C‐reactive protein (CRP)/bone morphogenetic protein 4 (BMP4) signaling pathway mediates periodontitis‐associated anxiety‐like behaviors in rats. This molecular crosstalk along the periodontal‐hippocampal axis provides novel insights into the etiology and mechanisms of emotional disorders. However, several
Zhigang Chen, Xing Li
wiley   +1 more source