Results 111 to 120 of about 4,652,557 (359)

Improvements in Health‐Related Quality of Life with Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post‐hoc Analysis of a Randomized Multicenter Trial

open access: yesArthritis Care &Research, Accepted Article.
Background While treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL change.
Austin Barry   +16 more
wiley   +1 more source

The effects of interventions targeting multiple health behaviors on smoking cessation outcomes: a rapid realist review protocol

open access: yesSystematic Reviews, 2018
Background Health behaviors directly impact the health of individuals, and populations. Since individuals tend to engage in multiple unhealthy behaviors such as smoking, excessive alcohol use, physical inactivity, and eating an unhealthy diet ...
Nadia Minian   +12 more
doaj   +1 more source

An Analysis of the UK and US on the Perceived Adequacy of Workplace Mental Health Programs [PDF]

open access: yes, 2020
An Analysis of the UK and US on the Perceived Adequacy of Workplace Mental Health Programs Julia Woods, Depts. of Business and Psychology, with Dr Deborah DiazGranados, VCU School of Medicine Research examining employee provided health benefits typically
Woods, Julia
core   +1 more source

Serum uric acid levels in older adults: Associations with clinical outcomes and implications for reference intervals in those aged 70 years and over

open access: yesArthritis Care &Research, Accepted Article.
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard   +15 more
wiley   +1 more source

Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration

open access: yesArthritis Care &Research, Accepted Article.
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget   +7 more
wiley   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

open access: yesAdvanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang   +13 more
wiley   +1 more source

Acceptability of Internet-based interventions for problem gambling: a qualitative study of focus groups with clients and clinicians

open access: yesBMC Medical Informatics and Decision Making, 2019
Background Although Internet-based interventions (IBIs) have been around for two decades, uptake has been slow. Increasing the acceptability of IBIs among end users may increase uptake.
Sherald Sanchez   +6 more
doaj   +1 more source

Disparities in Child and Adolescent Mental Health and Mental Health Services in the U.S. [PDF]

open access: yes, 2015
This is one of a series of five papers outlining the particular domains and dimensions of inequality where new research may yield a better understanding of responses to this growing issue.Mental health is recognized as a central determinant of individual
Jennifer Greif Green   +3 more
core  

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

open access: yesAdvanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi   +4 more
wiley   +1 more source

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