Results 111 to 120 of about 3,786,723 (290)

1054 Serum cytokine kinetics in C57BL/6 versus BALB/c mice upon Con A and LPS stimulation in vivo

open access: yesJournal for ImmunoTherapy of Cancer, 2023
Yi Li   +5 more
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Neutrosophic Logic for Mental Model Elicitation and Analysis [PDF]

open access: yesNeutrosophic Sets and Systems, 2014
Mental models are personal, internal representations of external reality that people use to interact with the world around them. They are useful in multiple situations such as muticriteria decision making, knowledge management, complex system learning ...
Karina Pérez-Teruel   +1 more
doaj  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Evaluating the Application of the Mental Model Mapping Tool (M-Tool). [PDF]

open access: yesFront Psychol, 2021
van den Broek KL   +3 more
europepmc   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara   +18 more
wiley   +1 more source

14 Humanized TFR1/CD71 knockin mouse model enables in vivo assessment of TFR1-targeted antibody therapies for cancer and beyond to across the blood-brain barrier

open access: yesJournal for ImmunoTherapy of Cancer, 2023
Yi Li   +7 more
doaj   +1 more source

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