Results 51 to 60 of about 170,433 (264)

Associations Between Biomarkers of Alzheimer's Disease and Sleep in Cognitively Unimpaired Older Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter   +5 more
wiley   +1 more source

Sphingomyelinase activity at pH 7.4 in human brain and a comparison to activity at pH 5.0

open access: yesJournal of Lipid Research, 1976
A hitherto undescribed sphingomyelinase (sph'ase 7.4) of human brain has been studied in crude and partially purified (3- to 4- fold) extracts of grey matter, and compared to the known sphingomyelinase with an acid pH optimum (sph'ase 5.0).
B G Rao, Dr M W Spence
doaj   +1 more source

Parkinson Disease Subtype Stability and Eventual Convergence

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous research identified distinct Parkinson disease (PD) clinical subtypes of “Motor Only,” “Psychiatric & Motor,” and “Cognitive & Motor” based on comprehensive, multidomain classification. Whether these subtypes reflect distinct trajectories or progressive disease stages remains unknown.
Laura M. Rosok   +10 more
wiley   +1 more source

MORPHOFUNCTIONAL AND PSYCHOPHYSIOLOGICAL FEATURES IN CHILDREN WITH INTELLECTUAL DISORDERS

open access: yesВестник Кемеровского государственного университета, 2017
The article studies morphofunctional and psychophysiological features in children with mental disabilities. The research features 7–9-year-old children, both male and female, with different central nervous system diseases (various degrees of mental ...
Nina G. Blinova   +2 more
doaj   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein   +7 more
wiley   +1 more source

Epilepsy and Mental Retardation

open access: yesPediatric Neurology Briefs, 1991
The cumulative risk of seizures and epilepsy was studied in a prospectively identified cohort of 221 children with mental retardation born between 1951 and 1955 in Aberdeen, Scotland and reported from the Montefiore-Einstein Epilepsy Management Center ...
J Gordon Millichap
doaj   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell   +2 more
wiley   +1 more source

Judge's Assessment of the Statement of a Witness Victim with Mental Retardation in a Rape Case

open access: yesIus Poenale, 2020
Victim witness testimony in a trial has an important role in proving a case, in this case the judge uses the testimony of a witness with a mental retardation as evidence for witness testimony.
Astri Wijayanti
doaj   +1 more source

Unsupervised Machine Learning Identifies Shared Biomechanical and Clinical Variation in Individuals with Knee Osteoarthritis and High BMI: A Secondary Analysis of the IDEA Trial

open access: yesArthritis Care &Research, Accepted Article.
Objective High body mass index (BMI≥27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck   +10 more
wiley   +1 more source

Causes of Mental Retardation

open access: yesPediatric Neurology Briefs, 1989
The mechanisms of mental retardation with relative prevalence in a hospital referral experience are reported from the Developmental Evaluation Clinic, Children's Hospital, Boston, MA.
J Gordon Millichap
doaj   +1 more source

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