Results 51 to 60 of about 62,846 (262)

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

Advanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang, Zuomeng Wu, Ruocheng Guo, Cancan Wang, Yue Qin, Yixiang Dong, Aoyun Li, Ao Liu, Chongyu Jia, Tianyu Han, Peiwen Song, Lei Chen, Cailiang Shen   +12 more
wiley   +1 more source

Bacterial population succession and adaptation affected by insecticide application and soil spraying history

Frontiers in Microbiology, 2014
Although microbial communities have varying degrees of exposure to environmental stresses such as chemical pollution, little is known on how these communities respond to environmental disturbances and how past disturbance history affects these community ...
Hideomi eItoh, Ronald eNavarro, Kazutaka eTakeshita, Kanako eTago, Masahito eHayatsu, Tomoyuki eHori, Yoshitomo eKikuchi   +6 more
doaj   +1 more source

Gas-Sensing Performances of Metal Oxide Nanostructures for Detecting Dissolved Gases: A Mini Review

Frontiers in Chemistry, 2020
Gas sensors have been wildly used in various fields related to people's lives. Gas sensor materials were the core factors that affected the performances of various gas sensors, and these have attracted much attention from scientific researchers due their
Wei Guan, Wei Guan, Na Tang, Kuang He, Kuang He, Xiaoying Hu, Xiaoying Hu, Mingshan Li, Mingshan Li, Kaiming Li, Kaiming Li   +10 more
doaj   +1 more source

Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulation. [PDF]

PLoS ONE, 2011
Deliberate and natural outbreaks of infectious disease, the prevalence of antibiotic resistant strains, and the ease by which antibiotic resistant bacteria can be intentionally engineered all underscore the necessity of effective vaccines and continued ...
Arthur Tsang, Heather Seidle, Safdar Jawaid, Weidong Zhou, Clint Smith, Robin D Couch   +5 more
doaj   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

The prediction of intraoperative cervical cord function changes by different motor evoked potentials phenotypes in cervical myelopathy patients

BMC Neurology, 2020
Background Surgery is usually the treatment of choice for patients with cervical compressive myelopathy (CCM). Motor evoked potential (MEP) has proved to be helpful tool in evaluating intraoperative cervical spinal cord function change of those patients.
Shujie Wang, Zhifu Ren, Jia Liu, Jianguo Zhang, Ye Tian   +4 more
doaj   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Precision scores of PBMR, REP, and MEP.

, 2018
Precision scores of PBMR, REP, and MEP.
Ali Hakan Ulusoy (5058869), Ahmed Mohamed Ahmed (5058875), Ahmet Rizaner (5058872)   +2 more
core   +1 more source

TMS MEP waveforms, cortical excitability.

, 2022
MEP waveforms for Experiment 2 for each subject. MEPs measured before (blue) and after (green) tUS exposure. (a) All waveforms. (b) Averaged waveforms. (TIF)
Tiffany K. Fan (12436762), Andrew C. Charles (12436771), Ian S. Heimbuch (12436759), Allan D. Wu (12436765), Marco Iacoboni (34305), Guido C. Faas (12436768)   +5 more
core   +1 more source

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source