Results 261 to 270 of about 802,927 (358)

Evaluation of trace element in the hair and nail samples of conventional and organic farmers in pesticide-treated highland villages. [PDF]

Environ Geochem Health
How V, Wong WV, Leong JY, Robun C, Anual ZF.   +4 more
europepmc   +1 more source

A Compartmentalized Joint‐on‐chip (JoC) Model to Unravel the Contribution of Cartilage and Synovium to Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
A compartmentalized joint‐on‐chip (JoC) platform is here developed, modelling the interactions between cartilage and synovium in osteoarthritis (OA). Using independent culture and mechanical/biochemical stimulation, the JoC revealed how inflammation and mechanical damage drive mutual tissue changes.
Cecilia Palma, Shima Salehi, Michela Anna Polidoro, Matteo Moretti, Marco Rasponi, Silvia Lopa, Paola Occhetta   +6 more
wiley   +1 more source

Composting as a Sustainable Approach for Managing Mercury-Contaminated Aquatic Biomass. [PDF]

Toxics
Caraballo-Laza MJ, Ossa-Henao DM, Urango-Cardenas I, Rosso-Pinto M, Guimarães JRD, Paternina-Uribe R, Palacios-Torres Y, Marrugo-Negrete J.   +7 more
europepmc   +1 more source

Islands in the Grey Area

, 2020
Milner, Amy
core  

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Biomarkers for tracking metabolic changes pre-post nutritional epigenetics diet/intervention to prevent autism and attention deficit/hyperactivity disorders in children. [PDF]

World J Exp Med
Dufault RJ.
europepmc   +1 more source

The Action of Mercury [PDF]

BMJ, 1873
openaire   +3 more sources

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang, Shengtao Cheng, Huiying Gu, Shan Zhong, Dapeng Zhang, Xin He, Weixian Chen, Haijun Deng, Jihua Ren, Peng Chen, Ming Tan, Hui Zhang, Fan Li, Zhenzhen Zhang, Yuan Hu, Juan Chen   +15 more
wiley   +1 more source

A Novel Approach to Estimate Mercury Exposure Risks Through Fish Consumption Based on the Selenium-Mercury Molar Ratio. [PDF]

Toxics
Cabral CDS, Monteiro LC, Maciel Pereira TA, da Costa Júnior WA, Oliveira IADS, Canela TA, Bernardi JVE, Pestana IA, Almeida R.   +8 more
europepmc   +1 more source