Results 151 to 160 of about 411,830 (306)

Policy responses to a dark side of the integration of regions [PDF]

In his paper I study policy responses to an increase in post-merger distress. I consider the integration of regions as a merger of populations which I view as a revision of social space, and I identify the effect of the merger on aggregate distress.
Stark, Oded
core  

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

The zCOSMOS redshift survey : Influence of luminosity, mass and environment on the galaxy merger rate

, 2011
The contribution of major mergers to galaxy mass assembly along cosmic time is an important ingredient to the galaxy evolution scenario. We aim to measure the evolution of the merger rate for both luminosity/mass selected galaxy samples and investigate ...
Abbas, U., Bardelli, S., Bolzonella, M., Bongiorno, A., Borgne, J. -F. Le, Bottini, D., Brun, V. Le, Cappi, A., Caputi, K., Carollo, C. M., Cassata, P., Cimatti, A., Contini, T., Coppa, G., Cucciati, O., de la Torre, S., de Ravel, L., Dunlop, J. S., Franzetti, P., Fumana, M., Fèvre, O. Le, Garilli, B., Guzzo, L., Iovino, A., Kampczyk, P., Kneib, J. -P., Knobel, C., Koekemoer, A. M., Kovac, K., Lamareille, F., Leauthaud, A., Lilly, S. J., Lopez-Sanjuan, C., Maccagni, D., Maier, C., Mainieri, V., Marinoni, C., McCracken, H. J., Memeo, P., Meneux, B., Mignoli, M., Montero, E. Perez, Oesch, P., Pello, R., Peng, Y., Porciani, C., Pozzetti, L., Renzini, A., Ricciardelli, E., Scaramella, R., Scarlata, C., Scodeggio, M., Silverman, J. D., Tanaka, M., Tasca, L., Tresse, L., Vergani, D., Zamorani, G., Zucca, E.   +58 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Osteopathic Otolaryngology Residency Match Trends: Impact of the ACGME Single Accreditation System (2010-2024). [PDF]

Spartan Med Res J
Reardon L, Knight B, Santiago-Rivera OJ, Shermetaro C.   +3 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Competition in human genetic technologies: The current US legal landscape. [PDF]

Am J Hum Genet
Rashid AI, Rincon NA, Rihani N, Wagner JK.   +3 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Understanding merger control remedies in China. [PDF]

PLoS One
Hu S, Gong J.
europepmc   +1 more source