Results 51 to 60 of about 104,344 (309)

Inner boundary reform in Košice: The most fragmented city in Slovakia [PDF]

open access: yesGeographica Pannonica, 2016
In the first part of the paper the aim is to provide the reader with a theoretical insight into models of government structure at the local level and provide evidence from European countries that underwent reforms during the second half of the 20th ...
Csachová Stela
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Leading Change and Restructuring the Manitoba Library Association

open access: yesPartnership: The Canadian Journal of Library and Information Practice and Research, 2020
Provincial and regional library associations provide the infrastructure for effective library advocacy, professional learning, development and networking, and help to lead libraries forward.
Alix-Rae Stefanko
doaj   +1 more source

Merger Failures [PDF]

open access: yesJournal of Economics & Management Strategy, 2005
This paper proposes an explanation as to why some mergers fail, based on the interaction between the pre-merger gathering of information and the postmerger integration processes. Rational managers acting in the interest of shareholders may still lead their firms into unsuccessfully integrated companies.
Banal-Estañol, A., Seldeslachts, J.
openaire   +9 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

How Effective is European Merger Control? [PDF]

open access: yes
This paper applies a novel methodology to a unique dataset of large concentrations during the period 1990-2002 to assess merger control’s effectiveness. By using data gathered from several sources and employing different evaluation techniques, we analyze
Gugler, Klaus   +2 more
core   +4 more sources

TAX ASPECTS REGARDING THE MERGER AND DIVISION [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014
In this paper, we want to present the tax issues that influencing the merger and division starting from the economic context characterized by a lack of liquidity, business reorganization to streamline the business and from the advantages and ...
BRAGĂ FILOFTEIA VIORICA   +1 more
doaj  

Mergers and Acquisitions

open access: yes, 2019
Abstract There are many types of mergers and acquisitions (M&A), be they a minority acquisition to explore a potential high growth emerging market, a takeover of a financially distressed firm with the aim of turning it around, or a private equity firm seeking short- to medium-term returns.
Pauliina Junni, Satu Teerikangas
openaire   +1 more source

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