Results 81 to 90 of about 19,139 (269)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
AimThe purpose of this study is to evaluate the influence of the merger process of two tertiary hospitals located in the northwest of Romania on the professional satisfaction among medical and non-medical staff and to develop a standardized satisfaction ...
Codrin Dan Nicolae Ilea +6 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Return on shares of steel companies under the influence of mergers and acquisitions
The present article intends to asses returns on shares of the steel companies that were formed based on either merger or acquisition. The analysis included 14 operations in the steel industry.
J. Zuzik +4 more
doaj
Economic Concentrations vs State of Competitive Space [PDF]
Achieving market performance is the main objective of companies in business transactions. Developing competitiveness and gaining a large market share is conditional on achieving the proposed objectives. A way to increase the market power is to do mergers
Caraganciu Anatolie, Tiuhtii Constanța
doaj
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
From Merger to Market Value: Short, Medium, and Long-Term Evidence from Bank Syariah Indonesia
The ability of bank mergers to generate sustained market value remains uncertain in emerging Islamic banking systems due to integration complexity, governance constraints, and heterogeneous investor expectations.
Mira Rahmi +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
This paper examines competition between groups of firms selling products that are complementary within the group but substitutes across groups. Examples include shops within different malls and components of different computer systems. It shows that firms within a group will often prefer to stay as separate companies rather than merge.
openaire +2 more sources

