Results 231 to 240 of about 9,409,817 (298)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Large Language Modeling-Enabled Analysis of Atrial Fibrillation on Social Media. [PDF]

J Am Heart Assoc
Parsa S, Somani S, Rogers AJ, Hernandez-Boussard T, Jain SS, Rodriguez F.   +5 more
europepmc   +1 more source

Real-time inference for binary neutron star mergers using machine learning. [PDF]

Nature
Dax M, Green SR, Gair J, Gupte N, Pürrer M, Raymond V, Wildberger J, Macke JH, Buonanno A, Schölkopf B.   +9 more
europepmc   +1 more source

Evidence for the first globular cluster stellar stream beyond the Milky Way. [PDF]

Nature
Holm JK, Pearson S, Nibauer J, Sand DJ, Price-Whelan AM, Starkenburg T, Hendel D, Fielder C.   +7 more
europepmc   +1 more source

Policy options for controlling rising hospital prices and their outcomes: a framework-based analysis. [PDF]

Health Econ Rev
Rezaei MA, Pourasghari H, Sari AA, Rezapour A.   +3 more
europepmc   +1 more source

Triangular fuzzy game modelling for internal innovation in platform-driven manufacturing enterprises under uncertainty. [PDF]

Sci Rep
Guo Y, Zhang H, Zou H, He D, Zhao C.
europepmc   +1 more source

Impact of COVID-19 measures on mental health, resilience and job satisfaction among healthcare professionals: A mixed-methods study

Schramade AE, Schaik MVv, Lavell AHA, Bomers MK, Pot MEvd, Tijdink JK, Sikkens JJ.   +6 more
europepmc   +1 more source