Results 61 to 70 of about 17,515,407 (332)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Article 22 EUMR and Call-in Powers as Tools of Jurisdictional Creep in Merger Control

open access: yesČasopis pro Právní Vědu a Praxi
This paper analyses the evolving use of Art. 22 EU Merger Regulation (EUMR) and national call-in powers as mechanisms for capturing below-threshold killer acquisitions.
Igor Kučera
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Impact of Horizontal Mergers on Rivals: Gains to Being Left Outside a Merger [PDF]

open access: yes, 2008
It is commonly perceived that firms do not want to be outsiders to a merger between competitor firms. We instead argue that it is beneficial to be a non-merging rival firm to a large horizontal merger. Using a sample of mergers with expert identification
Tomaso Duso   +4 more
core   +3 more sources

Issues of gender within the public interest sphere in South African merger reviews

open access: yesJournal of Economic and Financial Sciences
Orientation: Issues of gender are prominent in the global development agenda. Although South African competition law mandates that public interest considerations must be considered as part of merger decisions, gender considerations are not explicitly ...
Anton van Wyk   +2 more
doaj   +1 more source

Merger Control and the Public Interest: Balancing EU and National Law in the Protectionist Debate

open access: yes, 2014
In many jurisdictions across the world concern about foreign control of key national businesses appears to be mounting. This article examines the policies displayed towards foreign direct investment and cross-border mergers in the EU, focusing on the ...
Alison Jones, John Davies
semanticscholar   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Addressing the Impact of Foreign State-Owned Companies: Implications for Fair and Effective Merger Control

open access: yesYearbook of Antitrust and Regulatory Studies
State-owned firms from third countries play an increasingly significant role in international mergers and acquisitions, raising concerns about distortions of competition.
Annika Stöhr, Oliver Budzinski
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Non-competition Goals and Their Impact on South African Merger Control: An Empirical Analysis

open access: yesReview of Industrial Organization, 2022
Prince M. Changole, W. Boshoff
semanticscholar   +1 more source

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