Results 131 to 140 of about 59,175 (313)

Eat or be eaten: a theory of mergers and firm size [PDF]

open access: yes
We propose a theory of mergers that combines managerial merger motives and a regime shift that may lead to some value- increasing merger opportunities.
Gary Gorton   +2 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Spatial market expansion through mergers [PDF]

open access: yes
In this paper we present a model that studies firm mergers in a spatial setting. A new model is formulated that addresses the issue of finding the number of branches that have to be eliminated by a firm after merging with another one, in order to ...
Verónica Durán-Carbó   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

EUROPEAN CROSS-BORDER MERGERS AND ACQUISITIONS- REALITIES AND PERSPECTIVES [PDF]

open access: yes
This paper analyses the impact of the economic and financial crisis on merger and acquisition activity in Europe and the latest trends manifested on the cross-border merger and acquisition market involving European companies.
Vancea Mariana
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Effect of Mergers on the Incentive to Invest in Cost Reducing Innovations [PDF]

open access: yes
Both mergers and innovation are central elements of a firm?s competitive strategy. However, model-theoretical analyses of the merger-innovation link is sparse. The aim of this paper is to analyze the impact of mergers on innovative activities and product
Kleer, Robin
core   +2 more sources

ŞİRKET BİRLEŞMELERİ, BİRLEŞMELERDE TARİHSEL GELİŞİM SÜRECİ ve UYGULANAN ÖDEME YÖNTEMLERİ

open access: yesSosyal Ekonomik Araştırmalar Dergisi, 2010
Şirket birleşmeleri son yıllarda firmalar tarafından sıkça uygulanan bir dışsal büyüme şekli olarak karşımıza çıkmaktadır. Bununla birlikte, birleşmelerin yoğun bir şekilde yaşanması gerçekleşen tüm birleşmelerin başarılı olduğu anlamına gelmemelidir. Bu
İbrahim Erem Şahin, Baki Yılmaz
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Weddings with Uncertain Prospects – Mergers under Asymmetric Information [PDF]

open access: yes
We provide a framework for analyzing bilateral mergers when there is two-sided asymmetric information about firms’ types. We show that there is always a "no-merger" equilibrium where firms do not consent to a merger, irrespective of their type. There may
Thomas Borek   +2 more
core  

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