Results 221 to 230 of about 84,080 (312)

A prototype differential atom interferometer for fundamental physics. [PDF]

Nature
Baynham CFA, Hobson R, Buchmüller O, Evans D, Hawkins L, Iannizzotto Venezze L, Josset A, Lee D, Pasatembou E, Sauer BE, Tarbutt MR, Walker T, Ennis O, Chauhan U, Brzakalik A, Dey S, Hedges S, Stray B, Langlois M, Bongs K, Hird T, Lellouch S, Holynski M, Bostwick B, Chen J, Eyler Z, Gibson V, Harte TL, Hsu CC, Karzazi M, Lu C, Millward B, Mitchell J, Mouelle N, Panchumarthi B, Scheper J, Schneider U, Su X, Tang Y, Tkalčec K, Zeuner M, Zhang S, Zhi Y, Badurina L, Beniwal A, Blas D, Carlton J, Ellis J, McCabe C, Parish G, Govardhan DP, Vaskonen V, Bowcock T, Bridges K, Carroll A, Coleman J, Elertas G, Hindley S, Metelko C, Throssell H, Tinsley JN, Bentine E, Booth M, Bortoletto D, Callaghan N, Foot C, Gómez-Monedero C, Hughes K, James A, Leese T, Lowe A, March-Russell J, Sander J, Schelfhout J, Shipsey I, Weatherill D, Wood D, Balashov SN, Bason MG, Hussain K, Labiad H, Majewski P, Marchant AL, Newbold D, Pan Z, Tam Z, Thornton TC, Valenzuela T, van der Grinten MGD, Wilmut I, Clarke K, Vick A, AION Collaboration.   +92 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Merging public elementary schools to reduce racial/ethnic segregation. [PDF]

PNAS Nexus
Landry M, Gillani N.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Lean integration: A blueprint for occupational health services transformation in healthcare mergers. [PDF]

Healthc Manage Forum
Kestenberg S, Patel RH, Tan AO, De Graeve DC, Dhar A, Dus T.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Mechanical cues guide the formation and patterning of 3D spheroids in fibrous environments. [PDF]

PNAS Nexus
Sharma S, Agashe A, Hill JC, Ganguly K, Sharma P, Richards TD, Huang W, Kaczorowski DJ, Sanchez PG, Kapania R, Phillippi JA, Nain AS.   +11 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Public primary healthcare service network planning in Finland: a document analysis of principles, justifications, and future directions. [PDF]

Scand J Prim Health Care
Väisänen V, Tynkkynen LK, Sinervo T.
europepmc   +1 more source