Results 211 to 220 of about 128,002 (321)

Multi-messenger gravitational lensing. [PDF]

Philos Trans A Math Phys Eng Sci
Smith GP, Baker T, Birrer S, Collins CE, Ezquiaga JM, Goyal S, Hannuksela OA, Hemanta P, Hendry MA, Janquart J, Keitel D, Levan AJ, Lo RKL, More A, Nicholl M, Pastor-Marazuela I, Ponte Pérez AI, Ubach H, Uronen LE, Wright M, Zumalacarregui M, Bianco F, Çalişkan M, Chan JCL, Colangeli E, Gompertz BP, Haines CP, Hayes EE, Hu B, Lamb GP, Liu A, Mandhai S, Narola H, Nguyen QL, Poon JSC, Ryczanowski D, Seo E, Shajib AJ, Shan X, Tanvir N, Vujeva L.   +40 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Can digital M&As promote green innovation? Evidence from manufacturing companies in China. [PDF]

PLoS One
Wang X, Huang W.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Fragmenstein: predicting protein-ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding-based methodology. [PDF]

J Cheminform
Ferla MP, Sánchez-García R, Skyner RE, Gahbauer S, Taylor JC, von Delft F, Marsden BD, Deane CM.   +7 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Hospital Mergers, Hospital Choice, and Care Quality for Pregnant Enrollees in Medicaid.

JAMA Health Forum
Desai SM, Padmanabhan P, Glied S, Roberts ET.   +3 more
europepmc   +1 more source

Research on the impact of technology mergers and acquisitions on corporate performance: an empirical analysis based on China's pharmaceutical industry. [PDF]

Front Public Health
Yang J, Li J, Wang S, Chen Y.
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Corporate Activity - Mergers and Acquisition. [PDF]

Pharm Diagn Innov, 2005
europepmc   +1 more source