Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Cross-border mergers and acquisitions and the role of trade costs [PDF]
Cross-border mergers and acquisitions (M&As) have increased dramatically over the last two decades. This paper analyses the role of trade costs in explaining the increase in both the number and the value of cross-border mergers and acquisitions.
Alexander Hijzen +2 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
MERGERS AND ACQUISITIONS IN THE BANKING SECTOR OF THE REPUBLIC OF SERBIA
As a form of foreign direct investment, mergers and acquisitions have become an important form of cross-border investment in developing and transition countries since the last century.
Borjana Mirjanić +2 more
doaj +1 more source
INFLUENŢA LEGISLAŢIEI ASUPRA ACHIZIŢIILOR ŞI FUZIUNILOR BANCARE EUROPENE [PDF]
This paper looks at the number and value of Mergers and acquisitions that took place in the European Union financial industry in the 1990–2011 period. The process of mergers and acquisitions is the main method used by financial institution to grow and to
Andreea POPOVICI, Dragos TURLIUC
doaj
Do Foreign Mergers & Acquisitions Boost Firm Productivity? [PDF]
This paper examines the causal relationship between foreign mergers and acquisitions and firm productivity in the UK over the period 1999-2007. Our results raise questions about the existence of aggregate effects of foreign ownership on TFP in the longer-
Ruane, Frances +2 more
core
Analisis Perbandingan Kinerja Keuangan Perusahaan Sebelum dan Sesudah Merger dan Akuisisi pada Perusahaan Manufaktur yang Listing di BEI 2009-2012 [PDF]
This research aims to analyze the difference on firm performance before and after mergers and acquisitions a public company listed in Indonesia Stock Exchange.
L, A. (Al-azhar), Naziah, U. (Ulfathin)
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
VALUING THE IMPACT OF SYNERGIES ON PUBLIC MERGERS/ACQUSITIONS IN THE PHARMACEUTICAL SECTOR ON THE EUROPEAN CAPITAL MARKETS [PDF]
Valuing and identifying synergies in mergers and acquisitions is one of the important issues in Corporate Finance. The aim of this paper is to value the impact of synergies resulted from mergers/acquisitions in the European pharmaceutical sector ...
Oana Resceanu
core
Aggressive prostate cancer is associated with pericyte dysfunction
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source

