Results 41 to 50 of about 10,602 (218)
Strategi Penanganan Konflik pada Proses Penggabungan Perguruan Tinggi Swasta
: Merger of academies to be one university is a way to perform effectivity and efficiency of the foundation as the organizer of education. The process of conveying the idea will face challenges and conflicts such as opposition to the idea of merging ...
Nidya Dudija
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Precipitation is a crucial component of the water cycle and plays a key role in hydrological processes. Recently, satellite-based precipitation products (SPPs) have provided grid-based precipitation with spatiotemporal variability.
Giang V. Nguyen +5 more
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This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
A Metabolites Merging Strategy (MMS): Harmonization to Enable Studies’ Intercomparison
Metabolomics encounters challenges in cross-study comparisons due to diverse metabolite nomenclature and reporting practices. To bridge this gap, we introduce the Metabolites Merging Strategy (MMS), offering a systematic framework to harmonize multiple ...
Héctor Villalba +4 more
doaj +1 more source
Merging of Ontologies Through Merging of Their Rules
Ontology merging is important, but not always effective. The main reason, why ontology merging is not effective, is that ontology merging is performed without considering goals. Goals define the way, in which ontologies to be merged more effectively.
openaire +2 more sources
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
AbstractThis paper proposes a merge operator for behavioral requirements expressed by Message Sequence Charts and shows how this product can be systematically used to integrate new behaviors in an existing one. First the merge operator is defined as a fibered product of scenario descriptions. This product is then used to integrate a consensus mechanism
Jacques Klein +2 more
openaire +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source

