Results 41 to 50 of about 870 (213)

Biological fundamental functional units of meridians: mechanosensitive ion channels

Frontiers in Medicine
Meridians are central to the theory of Traditional Chinese Medicine (TCM), yet their biological essence remains elusive. Mechanosensitive ion channels (MS channels) respond to diverse physical stimuli, and their properties closely parallel the ...
Yiming Wang, Xiaojing Zhou, Songbin He
doaj   +1 more source

The Moxibustion-Induced Thermal Transport Effect Between the Heart and Lung Meridians With Infrared Thermography

Frontiers in Cardiovascular Medicine, 2022
ObjectivesBy comparing the differences in the thermal transport effect between the heart and lung meridians induced by moxibustion, this study aimed to investigate the specificity of site-to-site associations on the body surface between different ...
Xiaoyu Li, Xiaoyu Li, Yongliang Jiang, Hantong Hu, Jiali Lou, Yajun Zhang, Xiaofen He, Yuanyuan Wu, Junfan Fang, Xiaomei Shao, Jianqiao Fang   +10 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Short-term variation in ocular anterior chamber angle using Scheimpflug photography

African Vision and Eye Health, 2010
Purpose: To investigate short-term variation of ocular Anterior Chamber Angle (ACA) within and across the different meridians of young, healthy eyes. Method: Scheimpflug photography (via an  Oculus Pentacam) was used to repeatedly measure the anterior ...
A. Rubin
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Preliminary Analysis of the Relationship Between Acupoint Sensitivity and Inter-acupoint Distance Along the 12 Meridians

Journal of Acupuncture Research
Although the spatial organization of the acupoints is a fundamental element in acupuncture practice, its physiological relevance has not been fully established.
You-Jeong Han, Gyoungeun Park , Ga-young Kim, Jung-Eun Jang, Won-Suk Sung, Kyung-Ho Kim, Seung-Deok Lee   +6 more
doaj   +1 more source

Thickness profiles of the corneal epithelium along the steep and flat meridians of astigmatic corneas after orthokeratology

BMC Ophthalmology, 2020
Background The aim of this study was to investigate the changes in corneal epithelial thickness along the principle meridians of astigmatic corneas after six months of overnight spherical myopic orthokeratology (OK) lens wear.
Jiaqi Zhou, Feng Xue, Xingtao Zhou, Rajeev Krishnan Naidu, Yishan Qian   +4 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Comparison of Cutaneous Temperature at 12 Jing-well Points Regions of Bilateral Yin-and Yang-meridians in Healthy Volunteers

针刺研究, 2011
Objective To observe differences of cutaneous temperature of the 12 Jing-well points regions of the yin-meridians and yang-meridians,and on the upper and lower limbs so as to provide a reference for clinical diagnosis.Methods A total of 26 healthy young ...
LU Mei, ZHANG Bao-xun1, ZHAO Li-na1, CHEN Yi-lin1   +3 more
doaj  

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source