Results 101 to 110 of about 3,572 (228)

Avian neural crest cell attachment to laminin: involvement of divalent cation dependent and independent integrins [PDF]

, 1991
The mechanisms of neural crest cell interaction with laminin were explored using a quantitative cell attachment assay. With increasing substratum concentrations, an increasing percentage of neural crest cells adhere to laminin.
Bronner-Fraser, Marianne, Lallier, Thomas   +1 more
core  

ACTN3 Polymorphism Affects Thigh Muscle Area [PDF]

, 2010
Muscle mass is an important factor influencing the activity of daily living in older adults. We aimed to investigate whether α-actinin-3 (ACTN3) gene R577X polymorphism affects muscle mass in older Japanese women.
Iemitsu M., Kuno S., Maeda S., Murakami H., Tanabe K., Zempo H., 久野 譜也, 前田 清司   +7 more
core   +1 more source

SNP array typing provides new insights in chromosomal nondisjunction [PDF]

, 2017
Background Maternal uniparental disomy (UPD) of chromosome 7 (upd(7)mat) accounts for approximately 10% of patients with Silver-Russell syndrome (SRS).
Begemann, Matthias, Brioude, Frederic, Chantot-Bastaraud, Sandra, Eggermann, Thomas, Elbracht, Miriam, Graul-Neumann, Luitgard, Harbison, Madeleine, Netchine, Irene, Stratmann, Svea   +8 more
core   +1 more source

Aquatic physical therapy in the treatment of a child with merosin-deficient congenital muscular dystrophy: case report

Acta Fisiátrica, 2016
This case report describes an aquatic therapy program for a child with Merosin-Deficient Congenital Muscular Dystrophy. Objective: This study sought to investigate the effect of aquatic physical therapy on the speed and the rate of energy expenditure ...
Cinthya Patrícia de Albuquerque Santos, Ricardo Cristian Hengles, F. Cyrillo, F. M. Rocco, D. Braga   +4 more
semanticscholar   +1 more source

MUQIMIY IJODIY MEROSINING IQTISODIY AHAMIYATI

, 2023
{"references": ["1.\tMxmudov N.M , Avazov N,R. \"Muqimiyning iqtisodiy qarashlari\". Ilmiy risola. \u2013T. \"Iqtisodiyot\", 2021.- 56 bet. 2.\tO'zbekiston milliy ensiklopediyasi. Davlat ilmiy nashriyoti. Toshkent. 3.\tMuqimiy she'riyati matnida \"g'oyaviy tahrir\" masalasi // Oltin bitiklar.- Toshkent,2018. \u2013 No 1. \u2013 88-97."]}
openaire   +1 more source

Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies

Skeletal Muscle, 2011
Laminin-211 is a cell-adhesion molecule that is strongly expressed in the basement membrane of skeletal muscle. By binding to the cell surface receptors dystroglycan and integrin α7β1, laminin-211 is believed to protect the muscle fiber from damage under
Gawlik Kinga I, Durbeej Madeleine
doaj   +1 more source

Chimeric protein repair of laminin polymerization ameliorates muscular dystrophy phenotype [PDF]

, 2017
Mutations in laminin α2-subunit (Lmα2, encoded by LAMA2) are linked to approximately 30% of congenital muscular dystrophy cases. Mice with a homozygous mutation in Lama2 (dy2J mice) express a nonpolymerizing form of laminin-211 (Lm211) and are a model ...
Crosson, Stephanie C., McKee, Karen K., Meinen, Sarina, Reinhard, Judith R., Rüegg, Markus A., Yurchenco, Peter D.   +5 more
core   +1 more source

Novel mutation identification and copy number variant detection via exome sequencing in congenital muscular dystrophy

Molecular Genetics & Genomic Medicine, 2020
Background Congenital muscular dystrophy type 1A (MDC1A), also termed merosin‐deficient congenital muscular dystrophy (CMD), is a severe form of CMD caused by mutations in the laminin α2 gene (LAMA2). Of the more than 300 likely pathogenic variants found
Edmund S. Cauley, Alan Pittman, Swati Mummidivarpu, Ehsan G. Karimiani, Samantha Martinez, Isabella Moroni, Reza Boostani, Daniele Podini, Marina Mora, Yalda Jamshidi, Eric P. Hoffman, M. Chiara Manzini   +11 more
doaj   +1 more source

Expanding genotype/phenotype of neuromuscular diseases by comprehensive target capture/NGS [PDF]

, 2015
published_or_final_versio
Chen, WT, Chou, CH, Feng, Y, Hsu, YY, Huang, HD, Jong, YJ, Lam, CW, Liang, WC, Lin, TS, Tian, X, Wang, J, Wong, LJ, Zhang, VW   +12 more
core   +1 more source

Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy

Disease Models & Mechanisms, 2013
SUMMARY Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease for which there is no cure and limited treatment options. Prednisone is currently the first line treatment option for DMD and studies have demonstrated that it improves muscle ...
Ryan D. Wuebbles, Apurva Sarathy, Joe N. Kornegay, Dean J. Burkin   +3 more
doaj   +1 more source