Results 151 to 160 of about 444,796 (301)
Single-domain antibodies and their formatting to combat viral infections [PDF]
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies+4 more
core +2 more sources
Nucleotide‐bound crystal structures of the SARS‐CoV‐2 helicase NSP13
Nucleotide‐bound crystal structures of SARS‐CoV‐2 NSP13 capture a state immediately following ATP hydrolysis and reveal how crystal packing can affect structure‐based drug design targeting NSP13.Nucleotide‐bound crystal structures of SARS‐CoV‐2 NSP13 in ADP‐ and ATP‐bound states were resolved to 1.8 and 1.9 Å, respectively. The ADP‐bound model captures
Patrick Kloskowski+3 more
wiley +1 more source
ABSTRACT Background Nucleic acid amplification tests (NAATs) for human adenoviruses (HAdVs) causing respiratory infections usually target the hexon gene. However, new HAdV types with substantial variations in the hexon gene may not be detected. Thus, we focus on NAATs based on a conserved region in the penton gene to detect all HAdV types causing ...
Benedikt Beilstein+4 more
wiley +1 more source
Serological evidence of MERS-CoV and HKU8-related CoV co-infection in Kenyan camels
Dromedary camels are important reservoir hosts of various coronaviruses, including Middle East respiratory syndrome coronavirus (MERS-CoV) that cause human infections.
Wei Zhang+19 more
doaj +1 more source
The Hajj 2019 Vaccine Requirements and Possible New Challenges [PDF]
Each year millions of pilgrims perform the annual Hajj from more than 180 countries around the world. This is one of the largest mass gathering events and may result in the occurrence and spread of infectious diseases.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core +1 more source
ABSTRACT Aims To examine the relationship between hospital nurses' self‐perceived risk when caring for patients with infectious diseases and their moral distress, and how this relationship affects their emotional labour, while examining the moderating role of professional ethos.
Naimi Etti+2 more
wiley +1 more source
A novel human coronavirus was identified in Saudi Arabia and Qatar as the causative agent of severe acute respiratory diseases in 2012. The virus was termed Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and is taken notice of important coronavirus caused severe diseases to human after the outbreak of severe acute respiratory syndrome (SARS ...
openaire +3 more sources
Thus far, no human MERS-CoV infections have been reported from Israel. Evidence for the circulation of MERS-CoV in dromedaries has been reported from almost all the countries of the Middle East, except Israel.
Dan David+10 more
doaj
Spread of Mutant Middle East Respiratory Syndrome Coronavirus with Reduced Affinity to Human CD26 during the South Korean Outbreak [PDF]
The newly emerging Middle East respiratory syndrome coronavirus (MERS-CoV) causes a severe respiratory infection with a high mortality rate (similar to 35%).
Aigerim, A+16 more
core +1 more source
Analysis of Codon Usage and Nucleotide Bias in Middle East Respiratory Syndrome Coronavirus Genes
The Middle East Respiratory Syndrome (MERS) is an emerging disease caused by a recently identified human coronavirus (CoV). Over 2494 laboratory-confirmed cases and 858 MERS-related deaths have been reported from 27 countries.
Snawar Hussain+4 more
doaj +1 more source