Results 151 to 160 of about 444,796 (301)

Single-domain antibodies and their formatting to combat viral infections [PDF]

open access: yes, 2018
Since their discovery in the 1990s, single-domain antibodies (VHHs), also known as NanobodiesA (R), have changed the landscape of affinity reagents. The outstanding solubility, stability, and specificity of VHHs, as well as their small size, ease of ...
Ballegeer, Marlies   +4 more
core   +2 more sources

Nucleotide‐bound crystal structures of the SARS‐CoV‐2 helicase NSP13

open access: yesActa Crystallographica Section F, Volume 81, Issue 8, Page 338-347, August 2025.
Nucleotide‐bound crystal structures of SARS‐CoV‐2 NSP13 capture a state immediately following ATP hydrolysis and reveal how crystal packing can affect structure‐based drug design targeting NSP13.Nucleotide‐bound crystal structures of SARS‐CoV‐2 NSP13 in ADP‐ and ATP‐bound states were resolved to 1.8 and 1.9 Å, respectively. The ADP‐bound model captures
Patrick Kloskowski   +3 more
wiley   +1 more source

Development of a Rapid Isothermal Assay for Detection of Adenovirus Types Important in Respiratory Infections

open access: yesInfluenza and Other Respiratory Viruses, Volume 19, Issue 8, August 2025.
ABSTRACT Background Nucleic acid amplification tests (NAATs) for human adenoviruses (HAdVs) causing respiratory infections usually target the hexon gene. However, new HAdV types with substantial variations in the hexon gene may not be detected. Thus, we focus on NAATs based on a conserved region in the penton gene to detect all HAdV types causing ...
Benedikt Beilstein   +4 more
wiley   +1 more source

Serological evidence of MERS-CoV and HKU8-related CoV co-infection in Kenyan camels

open access: yesEmerging Microbes and Infections, 2019
Dromedary camels are important reservoir hosts of various coronaviruses, including Middle East respiratory syndrome coronavirus (MERS-CoV) that cause human infections.
Wei Zhang   +19 more
doaj   +1 more source

The Hajj 2019 Vaccine Requirements and Possible New Challenges [PDF]

open access: yes, 2019
Each year millions of pilgrims perform the annual Hajj from more than 180 countries around the world. This is one of the largest mass gathering events and may result in the occurrence and spread of infectious diseases.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

Caring for Patients With Infectious Diseases: Nurses' Risk Perception, Moral Distress, Professional Ethos and Emotional Labor: A Mixed Methods Study

open access: yesJournal of Clinical Nursing, Volume 34, Issue 8, Page 3133-3145, August 2025.
ABSTRACT Aims To examine the relationship between hospital nurses' self‐perceived risk when caring for patients with infectious diseases and their moral distress, and how this relationship affects their emotional labour, while examining the moderating role of professional ethos.
Naimi Etti   +2 more
wiley   +1 more source

A novel coronavirus, MERS-CoV

open access: yesUirusu, 2013
A novel human coronavirus was identified in Saudi Arabia and Qatar as the causative agent of severe acute respiratory diseases in 2012. The virus was termed Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and is taken notice of important coronavirus caused severe diseases to human after the outbreak of severe acute respiratory syndrome (SARS ...
openaire   +3 more sources

Middle East respiratory syndrome coronavirus specific antibodies in naturally exposed Israeli llamas, alpacas and camels

open access: yesOne Health, 2018
Thus far, no human MERS-CoV infections have been reported from Israel. Evidence for the circulation of MERS-CoV in dromedaries has been reported from almost all the countries of the Middle East, except Israel.
Dan David   +10 more
doaj  

Spread of Mutant Middle East Respiratory Syndrome Coronavirus with Reduced Affinity to Human CD26 during the South Korean Outbreak [PDF]

open access: yes
The newly emerging Middle East respiratory syndrome coronavirus (MERS-CoV) causes a severe respiratory infection with a high mortality rate (similar to 35%).
Aigerim, A   +16 more
core   +1 more source

Analysis of Codon Usage and Nucleotide Bias in Middle East Respiratory Syndrome Coronavirus Genes

open access: yesEvolutionary Bioinformatics, 2020
The Middle East Respiratory Syndrome (MERS) is an emerging disease caused by a recently identified human coronavirus (CoV). Over 2494 laboratory-confirmed cases and 858 MERS-related deaths have been reported from 27 countries.
Snawar Hussain   +4 more
doaj   +1 more source

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