Results 211 to 220 of about 467,339 (358)

COVID‐19‐Associated Cytotoxic Lesions of the Corpus Callosum in Chinese Patients: A Retrospective Study

open access: yesBrain and Behavior, Volume 15, Issue 6, June 2025.
We report the clinical characteristics, radiological features, and changes in inflammatory markers throughout the entire course of illness in eight patients with COVID‐19‐associated CLOCCs. The neurological symptoms or signs in these patients included altered consciousness, headache, cognitive impairment, ataxia, dysarthria, pyramidal signs, and visual
Chenyi Wan   +6 more
wiley   +1 more source

Peptide–Oligonucleotide Conjugates: Catalytic Preparation in Aqueous Solution or On‐Column

open access: yesCurrent Protocols, Volume 5, Issue 6, June 2025.
Abstract Peptide–oligonucleotide conjugates (POCs) are synthesized through a novel catalytic and sustainable approach. The amide coupling between peptide and oligonucleotide is facilitated by 1,4‐diazabicyclo[2.2.2]octane (DABCO) as catalyst and 2‐chloro‐4,6‐dimethoxy‐1,3,5‐triazine (CDMT) as a stoichiometric activating agent.
Marion Gras   +2 more
wiley   +1 more source

A novel genotyping system based on site polymorphism on spike gene reveals the evolutionary pathway of porcine epidemic diarrhea virus

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
This study focuses on porcine epidemic diarrhea virus (PEDV), a highly virulent and rapidly evolving coronavirus threatening global swine production. We established a novel genotype system of PEDV targeting site‐specific polymorphisms in the spike (S) protein.
Mingkai Lei   +10 more
wiley   +1 more source

Identification of potential SARS‐CoV‐2 genomic regions representing hallmarks for adaptation to different hosts

open access: yesiMetaOmics, Volume 2, Issue 2, June 2025.
The k‐mer‐based pipeline, namely the Pathogen Origin Recognition Tool using Enriched K‐mers (PORT‐EK) identifies genomic regions enriched in the respective hosts after the comparison of multi‐genomes of isolates between different host species. The enriched k‐mer counts, which may serve as a potential marker, enable the classification and prediction of ...
Janusz Wiśniewski, Heng‐Chang Chen
wiley   +1 more source

Cross-sectional study of MERS-CoV-specific RNA and antibodies in animals that have had contact with MERS patients in Saudi Arabia

open access: yesJournal of Infection and Public Health, 2018
Background: Middle East respiratory syndrome coronavirus (MERS-CoV) is a newly emerged coronavirus that is associated with a severe respiratory disease in humans in the Middle East. The epidemiological profiles of the MERS-CoV infections suggest zoonotic
Samy Kasem   +19 more
doaj  

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