Results 41 to 50 of about 4,805 (216)

Unmet Needs in Treatment Escalation for Chronic Spontaneous Urticaria: Findings From the CURE Registry

Allergy, EarlyView.
Appropriate treatment escalation improves CSU disease control. However, only about a quarter of patients achieve a complete response, the main goal of CSU treatment. Approximately one‐third of patients clinically eligible for escalation (UCT < 12) do not receive guideline‐recommended treatment escalation and remain symptomatic on their current ...
Pavel Kolkhir, Pascale Salameh, Magdalena Zajac, Alicja Kasperska‐Zajac, Ana Giménez‐Arnau, Maria Puertolas, Hanna Bonnekoh, Carolina Vera Ayala, Michael Makris, Eleni Chatzidimitriou, Stamatios Gregoriou, Kanokvalai Kulthanan, Andrea Bauer, Mojca Bizjak‐Suran, Daria Fomina, Alexis Bocquet, Joachim Dissemond, Mohamed Abuzakouk, Tara Raftery, Nadine Chapman‐Rothe, Emek Kocatürk, Clive Grattan, Riccardo Asero, Jonny G. Peter, Simon Francis Thomsen, Karsten Weller   +25 more
wiley   +1 more source

Digital mental health interventions as stand-alone vs. augmented treatment as usual

BMC Public Health
Background Smartphone-based digital mental health interventions (DMHI) have been described as a purported solution to meet growing healthcare demands and lack of providers, but studies often don’t account for whether patients are concurrently in another ...
Benjamin W. Nelson, Nicholas C. Peiper, Valerie L. Forman-Hoffman   +2 more
doaj   +1 more source

Analysis of Peripheral T Cell Profiling and Plasma Proteomics in Advanced NSCLC Patients Treated With Atezolizumab

Cancer Science, EarlyView.
This study found immune markers that may predict how well patients with advanced lung cancer respond to atezolizumab. Higher levels of certain T cells were linked to better survival. Specific patterns suggested a worse prognosis for some patients. ABSTRACT We investigated immunologic biomarkers that predict outcomes of patients with previously treated ...
Atsuto Mouri, Hiroshi Kagamu, Koji Tamada, Makoto Nishio, Hiroaki Akamatsu, Yasushi Goto, Hidetoshi Hayashi, Satoru Miura, Akihiko Gemma, Ichiro Yoshino, Toshihiro Misumi, Ryota Saito, Noriko Yanagitani, Fujita Masaki, Hiroshi Nokihara, Kazumi Nishino, Masahiro Seike, Tetsunari Hase, Osamu Hataji, Hiroaki Takeoka, Yosuke Kawashima, Hirotaka Kuroki, Masamichi Sugimoto, Hiroshi Kuriki, Tetsuya Mitsudomi   +24 more
wiley   +1 more source

Mathematical modeling and simulation of hepatitis B transmission dynamics with passive immunity and control strategies

Heliyon
Hepatitis B Virus (HBV) is a continued threat to mankind's health killing hundreds of thousands of people every year and thus calls for control and prevention measures to be put in place.
James Khobocha Mirgichan, Cyrus Gitonga Ngari, Stephen Karanja, Robert Muriungi   +3 more
doaj   +1 more source

Impact of Sequential Ramucirumab Plus Docetaxel After PD‐1 Inhibitors on Anti‐PD‐1 Antibody‐Bound T‐Cell Dynamics and Clinical Outcomes

Cancer Science, EarlyView.
Ramucirumab (RAM) plus docetaxel (DOC) after PD‐1 inhibitors showed clinical activity, with responders exhibiting maintained anti–PD‐1 (IgG4+)‐bound CD8+ T cells and decreased IgG4+ Tregs. A sequential strategy of administering RAM plus DOC during persistent anti–PD‐1 antibody binding may be beneficial in patients with advanced non‐small cell lung ...
Kinnosuke Matsumoto, Yujiro Naito, Takayuki Shiroyama, Motohiro Tamiya, Kazumi Nishino, Akihiro Tamiya, Kyoichi Okishio, Yuhei Kinehara, Tomoki Kuge, Masahide Mori, Shingo Satoh, Hidekazu Suzuki, Satoshi Tetsumoto, Toshie Niki, Yasuhiko Suga, Akio Osa, Toshiyuki Minami, Shohei Koyama, Yoshito Takeda, Nobuyuki Takakura, Atsushi Kumanogoh   +20 more
wiley   +1 more source

Modeling the effects of vaccine efficacy and rate of vaccination on the transmission of pulmonary tuberculosis

Informatics in Medicine Unlocked
Numerous prevention intervention strategies have been developed to curtail the spread of pulmonary tuberculosis to susceptible populations. However, pulmonary tuberculosis continues to claim many lives worldwide.
Erick Mutwiri Kirimi, Grace Gakii Muthuri, Cyrus Gitonga Ngari, Stephen Karanja   +3 more
doaj   +1 more source

Where water meets rock: Ecological niches and diversity hotspots of hygropetric beetles in the Neotropics

Ecological Entomology, EarlyView.
First continental‐scale synthesis of hygropetric beetle diversity and distribution across Neotropical highlands. Climatic and topographic gradients structure regional assemblages and niche overlap. Ecological convergence suggests adaptation to similar conditions across disjunct regions.
Janderson Batista Rodrigues Alencar, Fabrício Beggiato Baccaro, Cesar J. Benetti, Vinícius da Costa‐Silva, Neusa Hamada   +4 more
wiley   +1 more source

Relasi Kuasa, Mekanisme dan Strategi Meraih Kekuasaan dalam Program Social Forestry pada Taman Nasional Meru Betiri

Agriekonomika, 2018
Social forestry adalah upaya yang dilakukan untuk membuat masyarakat di sekitar hutan menjadi berdaya. Peneliti ingin mengungkap lebih jauh mengenai proses pemberdayaan dalam kerangka social forestry yang dilakukan terhadap masyarakat desa hutan di ...
Diah Puspaningrum, Ati Kusmiati
doaj   +1 more source

Tracheal collapse rates in Kenyan working cart and pack donkeys

Equine Veterinary Journal, EarlyView.
Abstract Background Donkeys (Equus asinus) in East Africa are recognised as working with poorly designed harnesses and carts. The donkey cart used in regions of Africa, specifically Meru County, Kenya, appears to place the cart's weight solely on the donkey's mid‐cervical region.
Martha Mellish, Jennifer Burns, Yvonne Elce, Jason W. Stull   +3 more
wiley   +1 more source

Critical Factors and Institutional Role in Strengthening Capacity of National Parks: Analysis of Meru Betiri National Park, Indonesia Using Interpretative Structural Modeling

Jurnal Manajemen Hutan Tropika, 2020
There are several factors suspected of ineffective rehabilitation and conservation of the Meru Betiri National Park. These important factors need to be identified to improve the management of the park.
Merry Muspita Dyah Utami, Hari Rujito, Hendra Yufit Riskiawan, Didiek Hermanuadi   +3 more
doaj   +1 more source