Results 121 to 130 of about 14,472 (257)

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Polygenic Risk Scores for Incident Dementia in the Multi-Ethnic Study of Atherosclerosis. [PDF]

Genet Epidemiol
Xue D, Blue EE, Sofer T, Hughes TM, Rotter JI, Post WS, Fohner AE.   +6 more
europepmc   +1 more source

Terrain Synthesis and Authoring based on Iso‐Contours

Computer Graphics Forum, EarlyView.
Abstract Digital terrains are central to realistic landscape depiction, yet authoring tools must balance perceptual realism with intuitive artistic control. We propose a compact vector‐based representation that models terrain as nested iso‐contours, inspired by geomorphology and cartography.
B. Huftier, H. Schott, E. Galin, O. Argudo, A. Peytavie, E. Guérin   +5 more
wiley   +1 more source

Giant Infrarenal Abdominal Aortic Aneurysm Treated With Elective Endovascular Repair Using an Anaconda Bifurcated Device: A Case Report. [PDF]

Cureus
Vargas OF, Salcedo-Mesa J.
europepmc   +1 more source

Authoring Terrestrial Planets with Diffusion Models

Computer Graphics Forum, EarlyView.
Abstract To support the design and subsequent generation of terrestrial planets for use in the creative media, we propose a solution that employs a generative model trained on satellite data from planetary bodies with a defined solid surface, such as the Earth and Mars.
Oliver Borg, James Gain, Éric Guérin, Adrien Peytavie, Marie‐Paule Cani, Eric Galin, Guillaume Cordonnier   +6 more
wiley   +1 more source

Scalable quantum photonic platform based on site-controlled quantum dots coupled to circular Bragg grating resonators. [PDF]

Light Sci Appl
Gaur K, Barua A, Tripathi S, Roche LJ, Wilksen S, Steinhoff A, Baraz S, Nitin N, Palekar CC, Koulas-Simos A, Limame I, Mudi P, Rodt S, Gies C, Reitzenstein S.   +14 more
europepmc   +1 more source

Scientists’ warning on the global destruction of rock outcrop ecosystems

Conservation Biology, EarlyView.
Abstract Rock outcrops are geological formations that harbor a highly specialized biota adapted to harsh environmental conditions that differ from their surrounding landscapes. They are globally distributed, especially in old, highly weathered landscapes, and can function as habitat islands containing high levels of endemism and distinct evolutionary ...
Luiza F. A. de Paula, Lucas N. Perillo, Gianluigi Ottaviani, Flávio F. Carmo, Mandar N. Datar, Katherine C. Enebeli‐Ekwutoziam, Bruno Fogliani, Stephen D. Hopper, Aboli Kulkarni, Hans Lambers, Rafael F. Magalhães, Frederico S. Neves, Jean‐François Ponge, Stefan Porembski, Bruno H. P. Rosado, Fernando M. G. Santos, Elycée Tindano, Bram Vanschoenwinkel, Aparna Watve, Fernando A. O. Silveira   +19 more
wiley   +1 more source

Data Consistency and Interpretation of Interleukin-6 and Cardiovascular Outcomes in MESA. [PDF]

JACC Adv
Tanaka K, Sata M.
europepmc   +1 more source

1170. Allium kollmannianum Brullo, Pavone & Salmeri

Curtis's Botanical Magazine, EarlyView.
Summary Allium kollmannianum is a small, late‐spring to early‐summer blooming Allium, endemic to the Negev Desert in south Israel, and previously thought to be extremely rare and critically endangered. Here we expand new information regarding its distribution and habitat in the Negev Desert, and a new estimation of its threat level, considering the new
Dar Ben‐Natan, Irene Blecher
wiley   +1 more source

Multi-Organ Physiologic Deficits During Exercise Identify Clinical and Molecular Predisposition to Heart Failure with Preserved Ejection Fraction. [PDF]

Circulation
Landsteiner I, Stolze LK, Peterson TE, Perry A, Lin P, Sheng Q, Zhao S, Amancherla K, Mi MY, Ikoma T, Cohen LP, Giverts I, Campain J, Lima JAC, Post WS, Taylor KD, Gerszten R, Rich SS, Tracy R, Durda P, Wood AC, Malhotra R, Rotter JI, Clish C, Nayor M, Gamazon ER, Shah RV, Lewis GD.   +27 more
europepmc   +1 more source