Results 231 to 240 of about 14,200 (285)

The Association of Mesalamine With Kidney Disease

Advances in Chronic Kidney Disease, 2020
The package inserts for products containing 5-aminosalicylic acid, or mesalamine, include the following language regarding the risk of adverse kidney effects: "renal impairment, including minimal change nephropathy, acute and chronic interstitial nephritis, and rarely renal failure, has been reported in patients given products such as mesalamine ...
Avinash, Adiga, David S, Goldfarb
openaire   +2 more sources

Physiologically Based Biopharmaceutics Modeling Coupled with Biopredictive Dissolution in Development of Bioequivalent Formulation for Mesalamine Enteric Coated Tablet: A Tough Nut to Crack

AAPS PharmSciTech
Mesalamine is a locally acting anti-inflammatory drug used to treat mild to moderate ulcerative colitis. Because of complex formulation principle and high in vivo variability, development of bioequivalent formulation for mesalamine is challenging ...
Sivacharan Kollipara, Pankaj Kumar Prabhat, Paramita Saha, Saurabh Gupta, Venkat Ramana Naidu, Tausif Ahmed   +5 more
semanticscholar   +1 more source

Mesalamine-Loaded Microsponges as a Potential Strategy for Colon-Specific Anti-Inflammatory Therapy: Design and Evaluation

International Journal of Pharmaceutical Investigation
Background: This study aimed to develop an efficient drug delivery system targeting the colon to treat inflammatory conditions using mesalamine. The approach involved formulating microsponges with Eudragit polymers, focusing on assessing the in vitro ...
Naveena Katta, Ashwini Madhava, P. Sudheer   +2 more
semanticscholar   +1 more source

Determination of Mesalamine in Bulk and Suppository Dosage Forms through the Development and Validation of Stability- indicating RPHPLC Method

Current Pharmaceutical Analysis
In the current study, a simple and cost-effective stability-indicating RP-HPLC method was developed and validated to estimate the mesalamine from both bulk and pharmaceutical dosage forms.
Nilima Anil Chaudhari, N. Ranpise
semanticscholar   +1 more source

Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease.

Inflammatory Bowel Diseases, 2021
BACKGROUND Some patients with inflammatory bowel disease (IBD) who were under mesalamine treatment develop adverse reactions called "mesalamine allergy," which includes high fever and worsening diarrhea.
Kaoru Suzuki, Y. Kakuta, Takeo Naito, T. Takagawa, H. Hanai, H. Araki, Yu Sasaki, H. Sakuraba, M. Sasaki, T. Hisamatsu, S. Motoya, T. Matsumoto, Motoyuki Onodera, Y. Ishiguro, H. Nakase, A. Andoh, S. Hiraoka, M. Shinozaki, T. Fujii, T. Katsurada, Taku Kobayashi, M. Fujiya, T. Otsuka, N. Oshima, Yasuo Suzuki, Yuichirou Sato, R. Hokari, M. Noguchi, Y. Ohta, M. Matsuura, Y. Kawai, K. Tokunaga, Masao Nagasaki, Hisaaki Kudo, N. Minegishi, Daisuke Okamoto, Yusuke Shimoyama, Rintaro Moroi, Masatake Kuroha, H. Shiga, Dalin Li, D. McGovern, Y. Kinouchi, A. Masamune, K. Ikeya, A. Nishida, Shoko Nakagawa, M. Miura, T. Toyonaga, K. Onodera, M. Takahara, S. Yanai, S. Ishihara, M. Nagahori, K. Matsuoka, K. Arai, S. Mizuno, M. Naganuma, Shiro Nakamura, Tomoaki Ishikawa, Hiroki Nakajima, H. Terasaki, Rumiko Saito, I. Amemiya, H. Ohyama, Kai Korekawa, Hideya Iwaki, Sayumi Takahashi, Motoki Makuuchi, Y. Inomata, Fumiko Shimoda, Takahiro Takahashi, Kota Yano, Izuru Abe, T. Handa, Y. Masu, Kasumi Hishinuma, Y. Kanazawa, Tomoya Kimura, K. Negoro, Mai Kato   +80 more
semanticscholar   +1 more source

Mesalamine-Induced Granulomatous Hepatitis

American Journal of Gastroenterology, 1999
A 42-yr-old man with ulcerative colitis was admitted for investigation of prolonged fever associated with cholestatic liver tests. Endoscopic retrograde cholangiopancreatography demonstrated a normal biliary tree, and liver biopsy showed granulomata.
M, Braun, G M, Fraser, M, Kunin, F, Salamon, R, Tur-Kaspa   +4 more
openaire   +2 more sources

Novel Bioenhanced Curcumin With Mesalamine for Induction of Clinical and Endoscopic Remission in Mild-to-Moderate Ulcerative Colitis

Journal of Clinical Gastroenterology, 2020
Background and Aims: The aim of this study was to assess the efficacy and safety of a novel, hydrophilic, bioenhanced curcumin (BEC) as add-on therapy in inducing clinical and endoscopic remission in mild to moderately active ulcerative colitis (UC ...
R. Banerjee, P. Pal, A. Penmetsa, Pradip Kathi, Ganesh Girish, I. Goren, D. Reddy   +6 more
semanticscholar   +1 more source

Multicenter survey on mesalamine intolerance in patients with ulcerative colitis

Journal of Gastroenterology and Hepatology, 2020
Although oral mesalamine is the first‐choice drug for treating mild‐to‐moderate ulcerative colitis (UC), some patients show symptoms of intolerance, including exacerbation of diarrhea and abdominal pain.
S. Hiraoka, A. Fujiwara, T. Toyokawa, Reiji Higashi, Yuki Moritou, S. Takagi, K. Matsueda, Seiyuu Suzuki, J. Miyaike, T. Inokuchi, M. Takahara, J. Kato, H. Okada   +12 more
semanticscholar   +1 more source

Attitudes to Mesalamine Questionnaire: A Novel Tool to Predict Mesalamine Nonadherence in Patients with IBD

American Journal of Gastroenterology, 2014
Poor adherence to mesalamine is common and driven by a combination of lifestyle and behavioral factors, as well as health beliefs. We sought to develop a valid tool to identify barriers to patient adherence and predict those at risk for future nonadherence.A 10-item survey was developed from patient-reported barriers to adherence.
Moss, Alan, Lillis, Yvonne, Edwards George, Jessica B., Choudhry, Niteesh, Berg, Anders, Cheifetz, Adam, Horowitz, Gary Leigh, Leffler, Daniel   +7 more
openaire   +3 more sources

RP‐HPLC Method Development for Simultaneous Determination of Mesalamine and Quercetin in Pure Forms and in Solid Lipid Nanoparticle Formulations

Separation Science Plus
This study aimed to develop and validate a straightforward HPLC method for simultaneously estimating mesalamine and quercetin in both pure forms and solid lipid nanoparticle formulations.
Raj Kamal, Priyanka Paul, Debanjan Mukherjee, Thakur Gurjeet Singh, Rohit Bhatia, Ankit Awasthi   +5 more
semanticscholar   +1 more source