Results 131 to 140 of about 25,271 (310)

Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders

Bulletin of the Korean Chemical Society, EarlyView.
5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley   +1 more source

Isolated Corticospinal Tract Lesions as an Early Manifestation of Adrenoleukodystrophy in Children

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Purpose X‐linked adrenoleukodystrophy (ALD) encompasses a wide range of neurological manifestations, classically described as distinct phenotypes including childhood cerebral adrenoleukodystrophy and adult‐onset adrenomyeloneuropathy (AMN).
Elle Winter, Amanda Nagy, Yedda Li, Otto Rapalino, Catherine L. Becker, Joseph Locascio, Camilo Jaimes, Florian Eichler   +7 more
wiley   +1 more source

Propylparaben Induced Embryonic Developmental Abnormalities in Chicken (Gallus gallus gallus, Linnaeus 1758)

Veterinary Sciences and Practices
Propylparaben is widely used as a preservative in food, cosmetics, and pharmaceuticals. Concerns regarding its potential teratogenic effects have been raised.
Hendry Saragih, Shuha Ma'muriyah Halim, Siti Aeniah, Wiwin Ariesti, Fianicha Shalihah, Desti Rahmadian, Ardaning Nuriliani   +6 more
doaj   +1 more source

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

Embryonic and mature astrocytes exert different effects on neuronal growth in rat ventral mesencephalic slice cultures. [PDF]

, 2015
One obstacle with grafting of dopamine neurons in Parkinson's disease is the insufficient ability of the transplant to reinnervate the host striatum. Another issue is the prospective interaction between the donor fetal tissue and the adult astrocytes of ...
Af Bjerkén, S, Hashemian, S, O'Rourke, C, Phillips, JB, Strömberg, I   +4 more
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Embryonic cerebrospinal fluid pressure in fetal mice in utero: External factors pressurize the intraventricular space

Developmental Dynamics, EarlyView.
Abstract Background Previous experiments inducing leakage of embryonic cerebrospinal fluid (CSF) suggest the necessity of intraventricular CSF pressure (PCSF) for brain morphogenesis. Nevertheless, how embryonic PCSF occurs is unclear, especially in utero. Results Using a Landis water manometer, we measured PCSF in fetal mice isolated from the amniotic
Koichiro Tsujikawa, Reina Muramatsu, Takaki Miyata   +2 more
wiley   +1 more source

Central nervous system. Sense organs [PDF]

, 2017
Навчальний посібник рекомендований для студентів вищих медичних навчальних закладів IV рівня акредитації, які вивчають анатомію людини англійською ...
Bumeister, Valentyna Ivanivna, Prykhodko, Olha Oleksiivna, Sulym, Liudmyla Hryhorivna, Yarmolenkо, Olha Serhiivna, Бумейстер, Валентина Ивановна, Бумейстер, Валентина Іванівна, Приходько, Ольга Алексеевна, Приходько, Ольга Олексіївна, Сулим, Людмила Григорьевна, Сулим, Людмила Григорівна, Ярмоленкo, Ольга Сергіївна, Ярмоленко, Ольга Сергеевна   +11 more
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Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell–cell junctions during neural tube formation

Developmental Dynamics, EarlyView.
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas, Brittany M. Hufft‐Martinez, Zarna Lalwani, Vi Pham, Mary Elmeniawi, An J. Tran, Jianming Xu, Irfan Saadi, Walid D. Fakhouri   +8 more
wiley   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Alteration of the in vivo nicotinic receptor density in ADNFLE patients: a PET study [PDF]

, 2017
Nicotinic acetylcholine receptors (nAChRs) are involved in a familial form of frontal lobe epilepsy, autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE).
Bottlaender, M., Brodtkorb, E., Bruel, D., Fruchart-Gaillard, C., Gambardella, A., Hufnagel, A., Picard, F., Roumenov, D., Saba, W., Schöllhorn-Peyronneau, M.-A, Servent, D., Steinborn, B., Valette, H., Zuberi, S.   +13 more
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