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The Concept of Mesenchymal Stem Cells

Regenerative Medicine, 2006
In this chapter we examine whether criteria usually defining adult tissue stem cells apply to mesenchymal stem cells (MSCs) that give rise to cells of the skeletal connective tissues. MSCs appear to constitute a heterogeneous population of undifferentiated and committed, lineage-primed cells, capable of: homing upon engraftment to a number of growth ...
SĂ©bastien Chateauvieux   +2 more
openaire   +3 more sources

Mesenchymal Stem Cells in Asthma

2019
Asthma is one of the worldwide respiratory health problem that affect children and adult. Current treatment strategies such as conventional and allergen immunotherapy still fall behind. Mesenchymal stem cells (MSCs) have wide regenerative capacity and immunoregulatory activity with their wide range of secretions and contact dependent manner.
openaire   +3 more sources

Mesenchymal Stem Cells

Bulletin of Experimental Biology and Medicine, 2002
I. V. Dubrovina   +3 more
openaire   +2 more sources

Fibroblast Looks Like a Mesenchymal Stem Cell and Talks Like a Mesenchymal Stem Cell: is It a Mesenchymal Stem Cell in Disguise?

2017
Induced Pluripotent Stem Cells (iPSCs) are adult somatic cells genetically reprogrammed to an embryonic stem cell-like state. Fibroblast (FB) is the adult somatic cell most commonly used for reprogramming and is defined by spindle-shape morphology, plastic-adherence and expression of several markers. Nonetheless, such properties also define Mesenchymal
Sacco A   +11 more
openaire   +2 more sources

Mesenchymal stem cells in osteoarthritis

Current Opinion in Rheumatology, 2004
Accumulating evidence indicates that every tissue contains stem cells. Our understanding of the biology of stem cells reveals that these cell populations have a critical role in the homeostasis and repair of tissues. Besides the local stem cell niches, additional compartments in the body such as the bone marrow may serve as reservoirs for stem cell ...
openaire   +3 more sources

Staging Soft Tissue Sarcoma: Evolution and Change

Ca-A Cancer Journal for Clinicians, 2006
Alexander J Lazar, Raphael Pollock
exaly  

Molecular mechanisms of epithelial–mesenchymal transition

Nature Reviews Molecular Cell Biology, 2014
Jian Xu, Rik Derynck
exaly  

Epithelial–mesenchymal transition: a new target in anticancer drug discovery

Nature Reviews Drug Discovery, 2016
Fabrizio Marcucci   +2 more
exaly  

Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets

Nature Reviews Drug Discovery, 2017
Yufang Shi, Liming Du, Liangyu Lin
exaly  

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