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The Concept of Mesenchymal Stem Cells
Regenerative Medicine, 2006In this chapter we examine whether criteria usually defining adult tissue stem cells apply to mesenchymal stem cells (MSCs) that give rise to cells of the skeletal connective tissues. MSCs appear to constitute a heterogeneous population of undifferentiated and committed, lineage-primed cells, capable of: homing upon engraftment to a number of growth ...
Sébastien Chateauvieux+2 more
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Mesenchymal Stem Cells in Asthma
2019Asthma is one of the worldwide respiratory health problem that affect children and adult. Current treatment strategies such as conventional and allergen immunotherapy still fall behind. Mesenchymal stem cells (MSCs) have wide regenerative capacity and immunoregulatory activity with their wide range of secretions and contact dependent manner.
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2017
Induced Pluripotent Stem Cells (iPSCs) are adult somatic cells genetically reprogrammed to an embryonic stem cell-like state. Fibroblast (FB) is the adult somatic cell most commonly used for reprogramming and is defined by spindle-shape morphology, plastic-adherence and expression of several markers. Nonetheless, such properties also define Mesenchymal
Sacco A+11 more
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Induced Pluripotent Stem Cells (iPSCs) are adult somatic cells genetically reprogrammed to an embryonic stem cell-like state. Fibroblast (FB) is the adult somatic cell most commonly used for reprogramming and is defined by spindle-shape morphology, plastic-adherence and expression of several markers. Nonetheless, such properties also define Mesenchymal
Sacco A+11 more
openaire +2 more sources
Mesenchymal stem cells in osteoarthritis
Current Opinion in Rheumatology, 2004Accumulating evidence indicates that every tissue contains stem cells. Our understanding of the biology of stem cells reveals that these cell populations have a critical role in the homeostasis and repair of tissues. Besides the local stem cell niches, additional compartments in the body such as the bone marrow may serve as reservoirs for stem cell ...
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Staging Soft Tissue Sarcoma: Evolution and Change
Ca-A Cancer Journal for Clinicians, 2006Alexander J Lazar, Raphael Pollock
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Molecular mechanisms of epithelial–mesenchymal transition
Nature Reviews Molecular Cell Biology, 2014Jian Xu, Rik Derynck
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Epithelial–mesenchymal transition: a new target in anticancer drug discovery
Nature Reviews Drug Discovery, 2016Fabrizio Marcucci+2 more
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Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets
Nature Reviews Drug Discovery, 2017Yufang Shi, Liming Du, Liangyu Lin
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