Results 21 to 30 of about 331,017 (218)
An aggressive angiomyxoma of vulva - A rare entity - A case report
Journal of Mid-Life Health, 2016 Aggressive angiomyxoma is a rare, locally invasive mesenchymal tumor predominantly presenting in women of reproductive age and also having a moderate-to-high risk for local relapse.
Bishnu Prasad Das +3 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Frontiers in OncologyBackgroundPerivascular epithelioid cell tumors (PEComas) are rare mesenchymal neoplasms with variable malignant potential, and gastrointestinal involvement is particularly uncommon.
Gizem Gunes, Adem Ozcan
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Cellular and Molecular Gastroenterology and HepatologyBackground & Aims: Tumor necrosis factor receptor 1 regulates intestinal epithelial survival and repair, yet its role in the colonic mesenchyme remains unclear.
Safina Gadeock +6 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Placental transmogrification of the lung: two case reports and a literature review
Frontiers in MedicineBackgroundPlacental transmogrification of the lung (PTL) is an uncommon benign lung lesion characterized by the presence of immature mesenchymal clear cells and frequent cystic changes.Case presentationWe report two cases.
Hong-yuan Zhou +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Dermatoscopic findings of atrophic dermatofibroma protuberans
Dermatology Practical & Conceptual, 2015 Dermatofibrosarcoma protuberans (DFSP) is an uncommon locally aggressive mesenchymal tumor with a high local recurrence rate. Atrophic DFSP is a rare variant of DFSP characterized by a non-protuberant lesion.
Bengu Nisa Akay +3 more
doaj +1 more source