Results 271 to 280 of about 99,415 (345)
STAT3 SH2 Domain Aspartic Acid 661 Mutations Activate Immune Gene Programs
Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.ABSTRACT The conserved aspartic acid residue D661 within the STAT3 SH2 domain is a recurrent mutational hotspot in hematologic malignancies, including T‐cell large granular lymphocytic leukaemia, myelodysplastic syndromes and acute lymphoblastic leukaemia. To define the functional consequences of distinct STAT3D661 variants, we integrated computational,
Hye Kyung Lee +10 more
wiley +1 more source
Somatostatin analogs in neuroendocrine tumors with Ki‐67 index of ≥10%
Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.Abstract Somatostatin analogs (SSAs) are an established first‐line therapy in intestinal and pancreatic neuroendocrine tumors (NETs). Based on Phase III studies, their use is recommended in NET with a Ki‐67 index of up to 10%. The effect of first‐line SSA therapy on differentiated NET with a Ki‐67 index ≥10% is poorly understood.
Johanna Braegelmann +6 more
wiley +1 more source
Hydrostatic Pressures in Lymphatic Networks of the Mouse
Microcirculation, Volume 33, Issue 1, January 2026.ABSTRACT Objective Current research on the lymphatic system makes nearly exclusive use of mouse models because that species is highly amenable to genetic manipulation. However, the lack of information about intraluminal hydrostatic pressures in mouse lymphatic networks limits the ability of investigators, for both in vivo and ex vivo studies, to ...
Michael J. Davis
wiley +1 more source
Multifocal Kaposiform Hemangioendothelioma Successfully Treated With Sirolimus Monotherapy
Pediatric Dermatology, Volume 43, Issue 1, Page 158-162, January/February 2026.ABSTRACT Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor that typically presents in infancy and may be associated with the Kasabach–Merritt phenomenon (KMP). We present a challenging case of multifocal KHE on the leg of an infant, initially suspected at birth to be a reticulate port wine birthmark.
Matthew J. Mahoney +8 more
wiley +1 more source
Two Cases of Mesenteric Lymph Node Abscess due to Yersinia Enterocolitica
, 2003 Akemi Yoshikawa +9 more
openalex +2 more sources
Histochemical and Immunohistochemical Identification of Mast Cells in the Rat Lacrimal Glands
Veterinary Ophthalmology, Volume 29, Issue 1, January 2026.ABSTRACT Objective This study aims to investigate the presence, microanatomical localization, and immunohistochemical subtypes of mast cells in the lacrimal glands (LGs) of rats. Animals A total of ten female Sprague–Dawley rats' LGs were evaluated in this study. Procedure(s) The experimental animals were euthanized. LG samples were collected and fixed
Ozkan Yavas
wiley +1 more source