Results 51 to 60 of about 79,258 (338)

Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs

Advanced Healthcare Materials, EarlyView.
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue‐like structures by self‐assembly into lymphatic bottom‐up tissues (lymphBUT) with tunable biochemical and biomechanical functionalities as well as metabolic activity are ...
Anna Burgstaller, Tamara Nink, Niklas Walter, Erick Angel Lopez Lopez, Hsin‐Fang Chang, Oskar Staufer   +5 more
wiley   +1 more source

Proteasome inhibitor bortezomib ameliorates intestinal injury in mice. [PDF]

PLoS ONE, 2012
BACKGROUND: Bortezomib is a proteasome inhibitor that has shown impressive efficacy in the treatment of multiple myeloma. In mice, the addition of dextran sulfate sodium (DSS) to drinking water leads to acute colitis that can serve as an experimental ...
Koichi Yanaba, Yoshihide Asano, Yayoi Tada, Makoto Sugaya, Takafumi Kadono, Shinichi Sato   +5 more
doaj   +1 more source

Myocardial infarction primes autoreactive T cells through activation of dendritic cells [PDF]

, 2017
Peripheral tolerance is crucial for avoiding activation of self-reactive T cells to tissue-restricted antigens. Sterile tissue injury can break peripheral tolerance, but it is unclear how autoreactive T cells get activated in response to self. An example
Bouché, Ann, Carmeliet, Peter, De Prijck, Sofie, Gillebert, Thierry, Guilliams, Martin, Lambrecht, Bart, Ludewig, Burkhard, Martens, Liesbet, Nindl, Veronika, Saeys, Yvan, Scott, Charlotte, Sichien, Dorine, Van Der Borght, Katrien, Van Moorleghem, Justine, Vanheerswynghels, Manon   +14 more
core   +6 more sources

Advanced Mounting Technique for Improved Imaging and Analysis of Embedded Spheroids and Migrating Cells in Light Sheet Fluorescence Microscopy

Advanced Materials Technologies, EarlyView.
A novel sample holder compatible with the Zeiss Lightsheet 7 microscope improves imaging of spheroids embedded in collagen matrices. By enabling dual‐sided illumination, it enhances image quality and quantitative analysis of migrating cells. This method advances 3D light sheet microscopy for studying tumor invasion and therapeutic responses.
Masoumeh Mohamadian Namaqi, Franziska Moll, Robert Römer, Andreas Grodrian, Doris Heinrich, Karen Lemke   +5 more
wiley   +1 more source

Immunohistochemical detection of CD3 and MAC387 antibodies in the mesenteric lymph nodes and the small intestine of 20 dogs that died of canine parvoviral enteritis

Macedonian Veterinary Review
There is little data on the use of the immunohistochemical method in the observation of the T lymphocytes and macrophages distribution within the mesenteric lymph nodes in canine parvovirus (CPV) enteritis.
Todor Novakov, Ivica Gjurovski, Spiro Bozinovski, Aleksandar Janevski, Nikola Adamov, Trpe Ristoski   +5 more
doaj   +1 more source

A Rare case of Carcinoid Tumour Presenting as an Acute Intestinal Obstruction with Cryptorchidism

Journal of Nepal Medical Association, 2013
A 40 year old man known to have cryptorchidism, presented with acute intestinal obstruction. At laparotomy stricture of the distal ileum, distended small intestine with enlarged multiple mesenteric and pelvic nodes were found.
Neelam R Charles, L B Christian, B Harishchandra, A Basu, P Sharma, G Krishnanand   +5 more
doaj   +1 more source

Evaluation and treatment decision of pancreatic tumors by use of MRI with MRCP imaging [PDF]

, 2009
Background: Pancreatic cancer is one of the most malignant tumors. Symptoms are usually nonspecific and insidious such that the cancer is advanced by the time of diagnosis.
Turowska, Aldona, Walecki, Jerzy, Łebkowska, Urszula   +2 more
core  

Simultaneous expression of CD4 and CD8 antigens by a substantial proportion of resting porcine T lymphocytes [PDF]

, 1987
The existence of four subpopulations in resting porcine T lymphocytes is documented. In addition to the two known subpopulations which are typified by a mutually exclusive expression of either the CD8 or the CD4 differentiation antigen, CD4-CD8+ and CD4 ...
Bevan, Bielefeldt Ohmann, Blue, Blue, Davignon, Fazekas de St. Groth, Goverman, Jonjić, Lanier, Lanier, MacDonald, Mackay, Pescovitz, Pescovitz, Reinherz, Reinherz, Saalmüller, Scollay, Swain, Tumbleson   +19 more
core   +3 more sources

ETV1 Drives CD4+ T Cell‐Mediated Intestinal Inflammation in Inflammatory Bowel Disease Through Amino Acid Transporter Slc7a5

Advanced Science, EarlyView.
This study identifies the transcription factor ETV1 as a key driver of CD4⁺ T cell‐mediated intestinal inflammation in inflammatory bowel disease (IBD). ETV1 promotes CD4⁺ T cell activation, proliferation, and Th17 differentiation by activating the amino acid transporter SLC7A5, fueling metabolic reprogramming.
Yan Shi, Song Wang, Yuqing Yan, Wei Chen, Yingying Cao, Dafan Chen, Wei Chen, Caiyun Ma, Xinjian Wan   +8 more
wiley   +1 more source

A case report of sigmoid colon cancer with the inferior mesenteric artery directly originating from the superior mesenteric artery

Surgical Case Reports, 2023
Background There are few reports describing the unusual origin of the inferior mesenteric artery (IMA). We report a rare case of advanced sigmoid colon cancer with the IMA arising from the superior mesenteric artery.
Kiyotaka Mizoguchi, Kinuko Nagayoshi, Yusuke Mizuuchi, Koji Tamura, Masafumi Sada, Kohei Nakata, Kenoki Ouchida, Masafumi Nakamura   +7 more
doaj   +1 more source