Results 141 to 150 of about 65,546 (307)

Immune Checkpoint Inhibitors Induce Intestinal Epithelial Injury and a Senescence‐Like Phenotype

iNew Medicine, EarlyView.
ICI treatment promotes the infiltration of activated immune cells into the intestinal mucosa. This inflammatory microenvironment is associated with significant epithelial injury, characterized by the disruption of the epithelial barrier, the depletion of specialized secretory cell lineages, and the induction of a premature senescence phenotype ...
Juan Wang, Shuang Wu, Shuangbiao Wei, Weizhen Xiang, Jianshang Huang, Lei Xiong, Hua Wang, Li Zuo   +7 more
wiley   +1 more source

Integrating Single‐Cell and Spatial Transcriptomes in HGSOC to Decipher the Metastasis‐Associated Biomarkers

iNew Medicine, EarlyView.
ABSTRACT High‐grade serous ovarian cancer (HGSOC) is the most common and lethal histological subtype of ovarian cancer. This study aimed to identify peritoneal metastasis‐associated biomarkers of HGSOC to provide directions for subsequent treatment. Transcriptome data were extracted from the GEO database and literature. Differential expression analysis,
Jing Zhu, Zhicheng Yu, Yang Zhang, Hui Hong, Xiaoli Wang, Shan Jiang, Ying Zhou, Cheng Peng, Hongbo Chen   +8 more
wiley   +1 more source

Transcranial Color‐Coded Duplex Sonography in Large‐Vessel Vasculitis Compatible With Takayasu Arteritis Presenting Intracranial Involvement and Vertebrobasilar Dolichoectasia: A Case Report

Journal of Clinical Ultrasound, EarlyView.
This case illustrates sequential intracranial occlusions in large‐vessel vasculitis compatible with Takayasu arteritis preserving perfusion through robust collateral pathways. Transcranial color‐coded duplex sonography identified characteristic blunted flow patterns and focal turbulence, underscoring its value in detecting hemodynamic compromise beyond
Maria Júnia Lira e Silva, Jordana Gaudie Gurian, Isabella Mesquita Venâncio, Eva Carolina Rocha, Gisele Sampaio Silva   +4 more
wiley   +1 more source

Status of Lymph Node Metastasis and Efficacy of Lymph Node Dissection Along the Superior Mesenteric Artery in Pancreatic Head Cancer: Clinicopathological Analysis of Patients Undergoing Pancreatoduodenectomy With Circumferential Lymph Nodes Dissection Along the Superior Mesenteric Artery

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Between 2002 and 2013, we performed pancreatoduodenectomy (PD) with combined resection of the superior mesenteric artery (SMA) (PD‐SMAR) to treat locally advanced pancreatic head cancer (PHC). Since 2011, we have performed PD with circumferential lymph node dissection along the SMA (PD‐CLDS), in which we dissected lymph nodes all ...
Isamu Makino, Hirohisa Kitagawa, Ryohei Takei, Kaichiro Kato, Satoshi Takada, Mitsuyoshi Okazaki, Yasuhito Iwao, Shinichi Nakanuma, Tetsuo Ohta, Shintaro Yagi   +9 more
wiley   +1 more source

Topological Complexity Determines the Frequency of Branching Variations in the Celiac Trunk–Superior Mesenteric Artery System

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Variations in the anatomical branching patterns of the celiac trunk and superior mesenteric artery (SMA) directly affect vascular identification, surgical planning, and risk of intraoperative vascular injury. However, despite the extensive classification of these variations, the principles governing the occurrence of certain ...
Satoru Muro, Akimoto Nimura, Keiichi Akita   +2 more
wiley   +1 more source

Diagnostic Performance of Ultrasound in Adult Appendicitis. A Retrospective Review of 331 Cases

Journal of Medical Radiation Sciences, EarlyView.
The sensitivity of ultrasound in the detection of appendicitis had a prevalence of 16% in our predominantly young female cohort, with alternative gynaecological and abdominal diagnoses identified approximately 2:1. The sensitivity for ultrasound to detect appendicitis was 60%, with specificity of 98% and negative predictive value (NPV) of 93%.
Alistair Lock, Martin Necas
wiley   +1 more source

Intrafraction motion and impact of margin reduction for MR‐Linac online adaptive radiotherapy for pancreatic cancer treatments

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 17-24, March 2025.
This analysis included quantification of intrafraction motion in pancreas stereotactic ablative radiotherapy treated on the MR‐Linac, leading to the development of adjusted (PTV) margins. Intrafraction motion indicated an average target displacement of 1–3 mm, resulting in an adjusted PTV margin of 2 mm in the right–left and superior–inferior ...
Ashleigh Fasala, Madeline Carr, Yolanda Surjan, Parmoun Daghigh, Jeremy de Leon, Abbey Burns, Vikneswary Batumalai   +6 more
wiley   +1 more source

Mesenteric Lymphangioma Presenting as Ileal Volvulus [PDF]

Journal of Clinical and Diagnostic Research, 2015
Harishkiran N Elukoti, Sulee Alcasoas, Jeevan Vernekar, Poonam Hegde, Sweta Pereira   +4 more
doaj   +1 more source

[Mesenterial fibromatosis].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1990
The article presents a case of a rare tumor, mesenteric fibromatosis, unassociated with Gardner's syndrome and without previously abdominal surgery. The author reviews symptoms, diagnostic features and treatment, and discusses some of the possible differential diagnoses.
openaire   +1 more source

The prognostic role of magnetic resonance enterography at diagnosis in paediatric isolated ileocaecal Crohn's disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives We aimed at identifying magnetic resonance enterography (MRE) predictors of surgical intervention and anti‐tumor necrosis factor alpha (TNF‐α) initiation in a paediatric cohort of patients newly diagnosed with isolated ileocaecal (L1) Crohn's disease (CD).
Saverio Pochesci, Luca Scarallo, Federico Rubera, Arianna Pranzetti, Marco Di Maurizio, Massimo Basile, Paolo Emilio Orlandi, Patrizia Alvisi, Paolo Lionetti   +8 more
wiley   +1 more source