Results 41 to 50 of about 79,010 (265)
EntropyImage stitching aims to synthesize a wider and more informative whole image, which has been widely used in various fields. This study focuses on improving the accuracy of image mosaic and proposes an image mosaic method based on local edge contour ...
Shaokang Ma +4 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Engineering ProceedingsThis paper presents the documentation, study activities, and possible applications of 3D digital models for the analysis and reconstruction of some examples of spheroidal stone projectiles—launched during the Sullan siege in 89 BC—now preserved in the ...
Silvia Bertacchi
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Real-Valued Optical Matrix Computing with Simplified MZI Mesh
Intelligent Computing, 2023 The Mach–Zehnder interferometer (MZI) mesh, a mainstream structure for optical matrix-vector multiplication (MVM), has been widely employed in recently developed optical neural networks (ONNs) and combination optimization problem solvers.
Bo Wu +7 more
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Towards optimal locality in mesh-indexings
Discrete Applied Mathematics, 1997 The efficiency of many data structures and algorithms relies on "locality-preserving" indexing schemes for meshes. We concentrate on the case where the maximal distance between two mesh nodes indexed i and j shall be a slow-growing function ...
Niedermeier, Rolf +2 more
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FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Shock and Vibration, 2005 This paper presents a reliable method of solution of two dimensional shape optimization problems subjected to transient dynamic loads using Genetic Algorithms. Boundary curves undergoing shape changes have been represented by B-splines.
Sabyasachi Chand, Anjan Dutta
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Optimal Angle Bounds for Quadrilateral Meshes [PDF]
Discrete & Computational Geometry, 2010 27 pages, 22 ...
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MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source