Results 81 to 90 of about 802,113 (294)
Decoupling simulation accuracy from mesh quality [PDF]
ACM Transactions on Graphics, 2018 For a given PDE problem, three main factors affect the accuracy of FEM solutions: basis order, mesh resolution, and mesh element quality. The first two factors are easy to control, while controlling element shape quality is a challenge, with fundamental limitations on what can be achieved. We propose to use p
Teseo Schneider +5 more
openaire +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Mesh smoothing algorithm based on exterior angles split.
PLoS ONE, 2020 Since meshes of poor quality give rise to low accuracy in finite element analysis and kinds of inconveniences in many other applications, mesh smoothing is widely used as an essential technique for the improvement of mesh quality.
Yongqing Hai +3 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Surface remeshing with robust user-guided segmentation
Computational Visual Media, 2018 Surface remeshing is widely required in modeling, animation, simulation, and many other computer graphics applications. Improving the elements’ quality is a challenging task in surface remeshing.
Dawar Khan +4 more
doaj +1 more source
BMC Gastroenterology, 2023 Background and aims Colonoscopy is the primary method to detect mucosal abnormalities in the colon, rectum, and terminal ileum. Inadequate bowel preparation is a common problem and can impede successful visualization during colonoscopy.
Christopher Kabir +3 more
doaj +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Gradient-Based Optimization of Linear Elasticity Mesh Deformation Quality
International Journal of Aerospace EngineeringMesh deformation based on the linear elasticity method is crucial in aerospace engineering research. However, maintaining mesh quality after significant deformations can be challenging.
Jinxin Zhou +5 more
doaj +1 more source