Results 61 to 70 of about 129,920 (270)

Research on tetrahedral adaptive mesh grading refinement for intersecting faults

Gong-kuang zidonghua
Current tetrahedral adaptive mesh refinement techniques have primarily focused on the 3D reconstruction and analysis of simple stratified geological bodies. When applying adaptive mesh refinement to complex geological structures, such as those containing
CHEN Yingxian, ZHU Zhe, MA Huiru, FU Jiepeng   +3 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Simulation Test of an Intelligent Vibration System for Concrete under Reinforcing Steel Mesh

Buildings
Concrete vibration construction sustains high labor intensity, a poor working environment, difficulties in quality control, and other problems. Current research on concrete vibration focuses on monitoring vibration quality, evaluating vibration processes
Hongyu Liang, Zhigang Wu, Jifeng Hu, Yuannan Gan, Sheng Qiang   +4 more
doaj   +1 more source

Cost-Utility Analysis of Open Hernia Operations in Bulgaria

Acta Medica Bulgarica, 2022
Background: Hernia surgery procedures are among the most frequently performed in Bulgaria. An open, mesh-based repair is a standard method for hernia repair.
Kirilova-Doneva M., Kamusheva M., Gerasimov N., Petrova G.   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

An adaptive mesh-based framework for real-time light fluence correction in photoacoustic tomography

Journal of Innovative Optical Health Sciences
Photoacoustic tomography (PAT), which combines excellent optical contrast with high acoustic resolution, has emerged as a promising medical imaging technique.
Long Chen, Zhaoyong Liang, Chaobin Hu, Jinchuan He, Anqi Wei, Li Qi   +5 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Development of the MPAS-CMAQ coupled system (V1.0) for multiscale global air quality modeling [PDF]

Geoscientific Model Development
The Community Multiscale Air Quality (CMAQ) model has been used for regulatory purposes at the U.S. EPA and in the research community for decades. In 2012, we released the Weather Research and Forecasting (WRF)-CMAQ coupled model that enables aerosol ...
D. C. Wong, D. C. Wong, J. Willison, J. E. Pleim, G. Sarwar, J. Beidler, R. Bullock, J. A. Herwehe, R. Gilliam, D. Kang, C. Hogrefe, G. Pouliot, H. Foroutan   +12 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source