Results 41 to 50 of about 2,438,793 (304)

Meshing Stiffness Calculation of Spur Bevel Gears Considering the Tooth Pair Coupling

open access: yesJixie chuandong, 2023
In order to solve the problem of calculation efficiency and accuracy of time-varying meshing stiffness of spur bevel gears, a slice calculation method of meshing stiffness of spur bevel gears considering the coupling effect of tooth pairs is proposed ...
Li Feifei, Dong Huimin, Zhang Chu
doaj  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

MESHING PERFORMANCE ANALYSIS OF TAPERED ROLLER ENVELOPING END FACE MESHING WORM DRIVE (MT) [PDF]

open access: yes, 2023
The end face meshing worm drive with tapered roller envelope has many simultaneous meshing tooth pairs and can eliminate clearance. According to the gear meshing principle and differential geometry principle, the meshing mathematical model of the ...
LIAO HongHui   +3 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Report of the Energy Efficiency Board. 2013. [PDF]

open access: yes, 2014
Annual; Began with 2010; ceased with 2011.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core  

Converting a tetrahedral mesh to a prism-tetrahedral hybrid mesh for FEM accuracy and efficiency [PDF]

open access: yesProceedings of the 2008 ACM symposium on Solid and physical modeling, 2008
AbstractThis paper presents a computational method for converting a tetrahedral mesh to a prism–tetrahedral hybrid mesh for improved solution accuracy and computational efficiency of finite element analysis. The proposed method performs this conversion by inserting layers of prism elements and deleting tetrahedral elements in sweepable sub‐domains, in ...
Soji Yamakawa, Kenji Shimada
openaire   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Energy Efficiency Board. 2015 Programs and operations report. [PDF]

open access: yes, 2016
Annual; Began with 2010; ceased with 2011.; At head of title: Connecticut Energy Efficiency ...
Connecticut. Energy Efficiency Board.
core  

Comparative Analysis of Meshing Characteristics Between Point-line Meshing Gears and Involute Gears [PDF]

open access: yes, 2023
Taking point-line meshing gears and involute gears as the research object, a simulation model of two kinds of meshing gears is established, the meshing characteristics of point-line meshing gears and involute gears in transmission error, tooth surface ...
Tang Yu   +3 more
core   +1 more source

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