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Surgical Considerations of Intractable Mesial Temporal Lobe Epilepsy
Surgery of temporal lobe epilepsy is the best opportunity for seizure freedom in medically intractable patients. The surgical approach has evolved to recognize the paramount importance of the mesial temporal structures in the majority of patients with ...
Warren W. Boling
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Familial Mesial Temporal Lobe Epilepsy
Clinical, genetic, and MR characteristics of 68 patients with familial mesial temporal lobe epilepsy (MTLE) were analysed at the University of Campinas-UNICAMP, Brazil.
J Gordon Millichap
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MicroRNAs as potential biomarkers in temporal lobe epilepsy and mesial temporal lobe epilepsy
Temporal lobe epilepsy is the most common form of focal epilepsy in adults, accounting for one third of all diagnosed epileptic patients, with seizures originating from or involving mesial temporal structures such as the hippocampus, and many of these ...
Bridget Martinez, Philip V Peplow
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Objective:This study aimed to determine the levels of monocyte/lymphocyte, neutrophil/lymphocyte, and platelet/lymphocyte (PLR) ratios in patients with mesial temporal lobe epilepsy, which is considered to be a chronic inflammatory brain disease, by ...
Aslı Bolayır
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Extrahippocampal temporal lobe atrophy in temporal lobe epilepsy and mesial temporal sclerosis [PDF]
Visual inspection and volumetric analysis of MRIs allow mesial temporal sclerosis (MTS) to be reliably identified in patients with temporal lobe epilepsy. The presence of unilateral MTS ipsilateral to the side of habitual seizure onset is an indicator for the prognosis of good outcome after temporal lobe resection.
N D Kitchen, D R Fish
exaly +3 more sources
Abstract Seizures commonly arise from the mesial temporal lobe, and “scarring” of the hippocampus, hippocampal sclerosis, is the commonest cause of drug-resistant epilepsy. Hippocampal sclerosis stems from genetic and environmental factors, including traumatic brain injury, prolonged seizures, or inflammation.
Nayak CS, Karsonovich T.
europepmc +2 more sources
Interstitial Thermal Therapy in Mesial Temporal Lobe Epilepsy.
ImportanceLaser interstitial thermal therapy (LITT) is a surgical tool used to ablate epileptic foci and brain tumors. Understanding clinical and procedural outcomes of LITT for mesial temporal lobe epilepsy (MTLE) is relevant to clinicians and patients.ObjectiveTo describe seizure outcomes, procedural outcomes, and safety data of MTLE LITT.Design ...
Landazuri P +20 more
europepmc +3 more sources
Prognostic factors in mesial temporal lobe epilepsy surgery [PDF]
Eighty-four patients submitted to anterior temporal lobectomy were evaluated retrospectively in order to correlate the different type of simple partial seizure (SPS) and their prognostic implications in patients with mesial temporal sclerosis.
DANIEL M. S. PREVEDELLO +2 more
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Whole-brain functional correlates of memory formation in mesial temporal lobe epilepsy
The mesial temporal lobe is a key region for episodic memory. Accordingly, memory impairment is frequent in patients with mesial temporal lobe epilepsy. However, the functional relevance of potentially epilepsy-induced reorganisation for memory formation
Anna Doll +7 more
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Non-lesional mesial temporal lobe epilepsy requires bilateral invasive evaluation
Purpose: Mesial temporal lobe epilepsy (MTLE) usually responds well to surgical treatment, although in non-lesional cases up to 50% of patients experience seizure relapse.
Ghazala Perven +12 more
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