Results 31 to 40 of about 11,014 (211)

Predictors of surgical outcomes in patients with drug-resistant temporal lobe epilepsy

open access: yesСеченовский вестник, 2022
Aim. To identify predictors of surgical outcomes in patients with drug-resistant temporal lobe epilepsy in a multivariate model.Materials and methods.
I. S. Shelyagin   +3 more
doaj   +1 more source

The interictal mesial temporal lobe epilepsy network

open access: yesEpilepsia, 2017
SummaryObjectiveIdentification of patient‐specific epileptogenic networks is critical to designing successful treatment strategies. Multiple noninvasive methods have been used to characterize epileptogenic networks. However, these methods lack the spatiotemporal resolution to allow precise localization of epileptiform activity.
Suganya, Karunakaran   +6 more
openaire   +3 more sources

Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen   +10 more
wiley   +1 more source

Spike Frequency and Surgical Outcome in TLE with Unilateral Hippocampal Atrophy

open access: yesPediatric Neurology Briefs, 2008
Prognostic implications of absolute spike frequency over the affected temporal lobe and relative spike distribution between the two temporal lobes for postoperative seizure control were assessed in 55 adult patients with medically refractory mesial ...
J Gordon Millichap
doaj   +1 more source

Disrupted causal connectivity in mesial temporal lobe epilepsy. [PDF]

open access: yesPLoS ONE, 2013
Although mesial temporal lobe epilepsy (mTLE) is characterized by the pathological changes in mesial temporal lobe, function alteration was also found in extratemporal regions. Our aim is to investigate the information flow between the epileptogenic zone
Gong-Jun Ji   +7 more
doaj   +1 more source

Refining Detection of Subclinical Epileptiform Activity in Alzheimer's Disease: A Case–Control Study and Call for a Consensus

open access: yesAnnals of Neurology, EarlyView.
Objective Sleep‐predominant network hyperexcitability is increasingly recognized as a potential disease‐accelerating comorbidity in Alzheimer's disease (AD). However, its prevalence and risk‐factors remain debated, largely due to cohort‐specific and methodological differences across studies.
Anna B. Szabo   +14 more
wiley   +1 more source

MRI and brain spect findings in patients with unilateral temporal lobe epilepsy and normal CT scan

open access: yesArquivos de Neuro-Psiquiatria, 1994
26 patients with temporal lobe epilepsy clinically documented by several abnormal interictal surface EEGs with typical unitemporal epileptiform activity and a normal CT scan were studied.
P.G. Carrilho   +8 more
doaj   +1 more source

Temporal Lobe Epilepsy and Psychiatric Comorbidity

open access: yesFrontiers in Neurology, 2021
Most focal seizures originate in the temporal lobe and are commonly divided into mesial and lateral temporal epilepsy, depending upon the neuronal circuitry involved.
Valerio Vinti   +7 more
doaj   +1 more source

Resolution of generalized tonic seizures following focal ablative or resective surgery

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Focal brain lesions may underlie generalized tonic seizures, as seen in Lennox–Gastaut syndrome, by engaging bilateral neural networks. However, this seizure type is often not considered surgically remediable. Here, we describe the resolution of apparent electroclinically classic generalized tonic seizures in children originating ...
Sem L. Kampman   +3 more
wiley   +1 more source

Temporal Lobe Malformations and Epilepsy

open access: yesPediatric Neurology Briefs, 1998
Temporal lobe developmental malformations (TLDM) (focal cortical dysplasia and balloon cells) occurred with mesial temporal sclerosis as dual pathologies in 87% of 30 patients with unilateral TLDM and intractable partial epilepsy treated at the UAB ...
J Gordon Millichap
doaj   +1 more source

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