Results 31 to 40 of about 23,412 (303)

Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]

open access: yes, 2014
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun   +3 more
core   +1 more source

Extrahippocampal temporal lobe atrophy in temporal lobe epilepsy and mesial temporal sclerosis [PDF]

open access: yesBrain, 2001
Visual inspection and volumetric analysis of MRIs allow mesial temporal sclerosis (MTS) to be reliably identified in patients with temporal lobe epilepsy. The presence of unilateral MTS ipsilateral to the side of habitual seizure onset is an indicator for the prognosis of good outcome after temporal lobe resection.
N F, Moran   +4 more
openaire   +2 more sources

Mesial temporal sclerosis presented with refractory seizure

open access: yesAPIK Journal of Internal Medicine, 2019
Background: Refractory complex partial seizures are common in temporal lobe epilepsy, which is often associated with sclerosis of the structures of the medial temporal lobes, particularly the hippocampus.
Malav Patel   +3 more
doaj   +1 more source

Structural imaging biomarkers of sudden unexpected death in epilepsy. [PDF]

open access: yes, 2015
Sudden unexpected death in epilepsy is a major cause of premature death in people with epilepsy. We aimed to assess whether structural changes potentially attributable to sudden death pathogenesis were present on magnetic resonance imaging in people who ...
Balestrini, Simona   +12 more
core   +3 more sources

Stereotactic Laser Ablation for Medically Intractable Epilepsy: The Next Generation of Minimally Invasive Epilepsy Surgery

open access: yesFrontiers in Surgery, 2016
Epilepsy is a common, disabling illness that is refractory to medical treatment in approximately one third of patients, particularly among those with mesial temporal lobe epilepsy.
Michael Joseph LaRiviere, Robert E Gross
doaj   +1 more source

Temporal plus epilepsy: the conception should be attack great importance and inquiring

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Mesial temporal lobe epilepsy (mTLE) is thought to be a network disease, most of them are medical intractable epilepsy. Surgery has benefit outcome, unfortunately, 20%-30% patients with mTLE who undergo surgery fail to achive seizure freedom.
WANG Wei⁃wei, WU Xun
doaj   +1 more source

Functional MRI during hippocampal deep brain stimulation in the healthy rat brain [PDF]

open access: yes, 2015
Deep Brain Stimulation (DBS) is a promising treatment for neurological and psychiatric disorders. The mechanism of action and the effects of electrical fields administered to the brain by means of an electrode remain to be elucidated.
Boon, Paul   +9 more
core   +3 more sources

Seizure clusters in drug-resistant focal epilepsy. [PDF]

open access: yes, 2016
We investigated clinical factors associated with seizure clustering in patients with drug-resistant focal epilepsy and any association between seizure clustering and outcome after surgery.
Asadi-Pooya   +12 more
core   +2 more sources

New Approaches to Studying Silent Mesial Temporal Lobe Seizures in Alzheimer's Disease

open access: yesFrontiers in Neurology, 2019
Silent seizures were discovered in mouse models of Alzheimer's disease over 10 years ago, yet it remains unclear whether these seizures are a salient feature of Alzheimer's disease in humans. Seizures that arise early in the course of Alzheimer's disease
Alice D. Lam   +5 more
doaj   +1 more source

Enhancing Safety in Epilepsy Surgery (EASINESS): Study Protocol for a Retrospective, Multicenter, Open Registry

open access: yesFrontiers in Neurology, 2021
Introduction: Optimizing patient safety and quality improvement is increasingly important in surgery. Benchmarks and clinical quality registries are being developed to assess the best achievable results for several surgical procedures and reduce ...
Richard Drexler   +50 more
doaj   +1 more source

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