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Heterozygous Variants in FREM2 Are Associated with Mesiodens, Supernumerary Teeth, Oral Exostoses, and Odontomas [PDF]

open access: goldDiagnostics, 2023
Background: Supernumerary teeth refer to extra teeth that exceed the usual number of dentitions. A mesiodens is a particular form of supernumerary tooth, which is located in the premaxilla region. The objective of the study was to investigate the genetic
Piranit Nik Kantaputra   +11 more
doaj   +5 more sources

Genetic Variants in Protein Tyrosine Phosphatase Non-Receptor Type 23 Are Responsible for Mesiodens Formation [PDF]

open access: yesBiology, 2023
A mesiodens is a supernumerary tooth located in the midline of the premaxilla. To investigate the genetic cause of mesiodens, clinical and radiographic examination were performed on 23 family members of a two-generation Hmong family.
Ploy Adisornkanj   +11 more
doaj   +3 more sources

Management of Impacted and Inverted Mesiodens - A Report of Two Cases

open access: yesJournal of Pharmacy and Bioallied Sciences
Supernumerary teeth represent a significant dental anomaly that has a notable impact on the primary and early mixed dentition, potentially leading to pathological disturbances in the development of permanent dentition. Mesiodens specifically refers to an
Vabitha Shetty   +4 more
doaj   +3 more sources

Mesiodens and paramolar in the medieval age skeletal remains [PDF]

open access: bronze, 2002
Evolution as in all segments of human behavior and existence has left traces on human teeth. The aim of this study was to determine the frequency of the supernumerary teeth in skeletal remains found at the archeological site Stara Torina and SEM ...
Tihaček-Šojić Ljiljana   +2 more
core   +3 more sources

Intraoral Approach Through the Nasal Floor for Surgical Removal of Inverted Mesiodens: Protocol and Case Series. [PDF]

open access: yesJ Clin Med
Background/Objectives: The most common form of supernumerary teeth is represented by the mesiodens. Very often, they are impacted, usually palatially, but can be found buccally or between the roots of the permanent central incisors. Their position can be
Urechescu H   +6 more
europepmc   +2 more sources

Image segmentation of impacted mesiodens using deep learning [PDF]

open access: bronzeJournal of Clinical Pediatric Dentistry
This study aimed to evaluate the performance of deep learning algorithms for the classification and segmentation of impacted mesiodens in pediatric panoramic radiographs.
Hyun-Tae Kim   +6 more
openalex   +2 more sources

DKK1 is a strong candidate for mesiodens and taurodontism

open access: greenClinical Genetics, 2023
A mutation in DKK1 gene leads to inhibitory DKK1 function, over-activation of WNT/β-catenin signaling, disruptive development of dental epithelium, and subsequent mesiodens formation.
Piranit Nik Kantaputra   +9 more
openalex   +3 more sources

Rare Variants in LRP4 Are Associated with Mesiodens, Root Maldevelopment, and Oral Exostoses in Humans [PDF]

open access: goldBiology, 2023
Simple Summary Low density lipoprotein receptor-related protein 4 (LRP4; MIM 604270) modulates WNT/β-catenin signaling, through its binding of WNT ligands, and to co-receptors LRP5/6, and WNT inhibitors DKK1, SOSTDC1, and SOST.
Piranit Nik Kantaputra   +10 more
openalex   +2 more sources

Anterior Maxillary Mesiodens Extraction in a Young Adult Male: A Case Report. [PDF]

open access: yesCureus
Mesiodens are classified as supernumerary teeth located in the maxilla, specifically in the palatal region between the central incisors. The prevalence of this condition varies between 0.15% and 1.9% among individuals.
Hemnani G   +5 more
europepmc   +2 more sources

Double Mesiodens in the Mixed Dentition of Non-syndromic North-Indian Patients: A Case Series. [PDF]

open access: yesCureus
The presence of double mesiodens or mesiodentes, i.e., two supernumerary teeth in the maxillary midline, presents unique challenges in mixed dentition. Common clinical manifestations include delayed eruption, midline diastema, and occlusal disturbances ...
Bhatara S   +4 more
europepmc   +2 more sources

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