Results 241 to 250 of about 68,662 (305)

Mitochondria‐Targeted Nanomotor: H2S‐Driven Cascade Therapy for Hepatocellular Carcinoma

Advanced Materials, Volume 38, Issue 8, 6 February 2026.
A mitochondrial‐targeted nanomotor integrates photodynamic therapy, mild photothermal therapy, and enzyme dynamic therapy into a self‐amplifying cascade through H2S‐driven metabolic reprogramming. Abstract Despite advances in combination therapies for cancer treatment, most strategies rely on modular‐additive designs that lack dynamic molecular cues to
Chengcheng Li, Xiaodong Ma, Shiji Fang, Biao Chen, Xinru Wang, Lingyun He, Xin Yang, Yuanqiang Li, Jessica M. Rosenholm, Zhongwei Zhao, Jiansong Ji, Hongbo Zhang   +11 more
wiley   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

Advanced Sensor Research, Volume 5, Issue 2, February 2026.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

Layer-by-Layer Assembled Nanocomposite Membranes with Functionalized Dendritic Mesoporous Silica Nanoparticles for Selective Heavy Metal Removal. [PDF]

ACS Omega
Alotaibi KM, Shukla AK, Alshahrani AA, Alzhrani EM, Alotaibi SS, Alswieleh A.   +5 more
europepmc   +1 more source

Spatiotemporally Controlled Tumor Photodynamic/Immunotherapy Therapy Based on Upconversion Hybrid Nanosystem

Advanced Science, Volume 13, Issue 7, 3 February 2026.
PURH is constructed by a five‐layer upconversion nanoparticle (UCNP) surface coated with mesoporous silica, which encapsulates rose bengal (RB) within the mesoporous channels. Additionally, CpG oligonucleotides (CpG ODN) is linked to the surface, followed by the surface functionalization of hyaluronic acid (HA). This spatiotemporally controllable smart
Fang Wang, Wenfei Xu, Yuechen Liu, Shuxuan Zhu, Wenjing Liu, Shuhui Bo, Hong Sun, Bei Liu, Zhaogang Sun, Hongqian Chu   +9 more
wiley   +1 more source

Mesoporous Silica Nanoparticles Impair Physiology and Reproductive Fitness of <i>Tuta absoluta</i> Through Plant-Mediated Oxidative Stress and Enzymatic Disruption. [PDF]

Insects
Haq IU, Liu H, Ghafar MA, Zafar S, Subhan M, Abbasi A, Hyder M, Basit A, Rebouh NY, Hou Y.   +9 more
europepmc   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

A Review on the Recent Advancements of Polymer-Modified Mesoporous Silica Nanoparticles for Drug Delivery Under Stimuli-Trigger. [PDF]

Polymers (Basel)
Santhamoorthy M, Asaithambi P, Ramkumar V, Elangovan N, Perumal I, Perumal I, Kim SC.   +6 more
europepmc   +1 more source

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu, Qiqing Huang, Yang Liu, Jinzhuo Liu, Deyi Yang, Yanni Song, Xin Han   +6 more
wiley   +1 more source

Magnetic mesoporous silica nanoparticles as advanced polymeric scaffolds for efficient cancer chemotherapy: recent progress and challenges. [PDF]

RSC Adv
Payamifar S, Khalili Y, Foroozandeh A, Abdouss M, Hasanzadeh M.   +4 more
europepmc   +1 more source