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Mesoporous Silica Nanoparticles: A Review
Journal of Developing Drugs, 2017One of the greatest challenges in the field of medicine is the effective and efficient drug delivery to the defected cells or tumor cells with minimal toxic side effects. Due to lacking properties like specification and solubility of drug molecule, patient requires high doses of the drug to attain the desired therapeutic effect for the disease ...
Asad Mehmood +4 more
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Mesoporous silica templated zirconia nanoparticles
Journal of Nanoparticle Research, 2010Nanoparticles of zirconium oxide (ZrO2) were synthesized by infiltration of a zirconia precursor (ZrOCl2·8H2O) into a SBA-15 mesoporous silica mold using a wet-impregnation technique. X-ray diffractometry and high-resolution transmission electron microscopy show formation of stable ZrO2 nanoparticles inside the silica pores after a thermal treatment at
Mohamed A. Ballem +2 more
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Modulating Osteoimmune Responses by Mesoporous Silica Nanoparticles
ACS Biomaterials Science & Engineering, 2021The immune response plays an important role in biomaterial-mediated osteogenesis. Nanomaterials may influence immune responses and thereby alter bone regeneration. Mesoporous silica nanoparticles (MSNs) have received much attention for drug delivery and bone regeneration. Recently, immunomodulatory effects of MSNs on osteogenesis have been reported. In
Sepanta Hosseinpour +2 more
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Biocompatibility of Mesoporous Silica Nanoparticles?
Comments on Inorganic Chemistry, 2015Mesoporous silica nanoparticles (MSNs) have been widely explored as drug delivery vehicles in cell and animal studies. To move this nanoparticle platform into the clinic, however, further work needs to be done to predict and assess potential adverse reactions and side-effects to optimize for their efficacious and safe use in patients.
Yi Shi +2 more
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Stable Silver Nanoparticles Immobilized in Mesoporous Silica
Chemistry of Materials, 2003Silver nanoparticles have been produced by -irradiation of silver solution in optically transparent inorganic mesoporous silica. The reduction of Ag+ within the matrix is brought about by hydrated electrons and hydroalkyl radicals generated during the radiolysis of the 2-propanol solution.
Hornebecq, Virginie +3 more
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Monodisperse mesoporous silica nanoparticles of distinct topology
Journal of Colloid and Interface Science, 2017Monodisperse and uniform high-quality MCM(Mobil Composition of Matter)-48-type CMSNs (Cubic Mesoporous Silica Nanoparticles) are readily prepared by simply optimizing the molar ratio of ethanol and surfactant in the system TEOS-CTAB-NaOH-H2O-EtOH (TEOS=tetraethyl orthosilicate, CTAB=cetyltrimethylammonium bromide, EtOH=ethanol).
Leilei, Luo +3 more
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Multifunctional Mesoporous Silica Nanoparticles for Biomedical Applications
2020Mesoporous silica nanoparticles (MSNs) are outstanding nanocarriers for drug delivery, imaging, and other biomedical applications. MSN features a well-defined mesoporous structure with tunable pore size, pore volume, high surface area, and high drug loading capacity and offers external and interior surfaces for functionalization over conventional ...
Aswathy Ravindran Girija +1 more
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Colloidal Suspensions of Functionalized Mesoporous Silica Nanoparticles
ACS Nano, 2008The synthesis and characterization of colloidal mesoporous silica (CMS) functionalized with vinyl-, benzyl-, phenyl-, cyano-, mercapto-, aminopropyl- or dihydroimidazole moieties is reported. Uniform mesoporous particles ranging in size from 40 to 150 nm are generated in a co-condensation process of tetraethylorthosilicate (TEOS) and ...
Johannes, Kobler +2 more
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Mesoporous‐Silica‐Functionalized Nanoparticles for Drug Delivery
Chemistry – A European Journal, 2015AbstractThe ever‐growing interest for finding efficient and reliable methods for treatment of diseases has set a precedent for the design and synthesis of new functional hybrid materials, namely porous nanoparticles, for controlled drug delivery. Mesoporous silica nanoparticles (MSNPs) represent one of the most promising nanocarriers for drug delivery ...
Simon, Giret +2 more
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Functionalized mesoporous silica nanoparticles and biomedical applications
Materials Science and Engineering: C, 2019Since the first report in early 1990s, mesoporous silica nanoparticles (MSNs) have progressively attracted the attention of scientists due to their potential applications in physic, energy storage, imaging, and especially in biomedical engineering. Owning the unique physiochemical properties, such as highly porosity, large surface area and pore volume,
Thai Thanh, Hoang Thi +5 more
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