Results 141 to 150 of about 107,800 (308)

Clinical significance and immune microenvironment association of cuproptosis‐related genes in pan‐cancer

open access: yesExperimental Physiology, EarlyView.
Abstract Recent studies highlight the important roles of cuproptosis in cancer cells. However, the roles of the cuproptosis‐related genes (CRGs) in different cancers are still not fully understood. Comprehensive analysis was performed using open‐source bioinformatic platforms to disclose the expression profiles, prognostic significance, genomic and ...
Xinyu Ge   +10 more
wiley   +1 more source

The public health impacts of mining in Australia

open access: yesMedical Journal of Australia, EarlyView.
Summary Australia is rich in minerals of commercial interest along with oil and gas, and mining activities are carried out in almost all states and territories. The public health impacts of mining on the Australian general population need to be addressed to enable a comprehensive cost–benefit assessment of these activities balanced against their ...
Javier Cortes‐Ramirez   +3 more
wiley   +1 more source

A case of ovarian mesothelioma with VHL mutation diagnosed by immunohistochemistry and literature review

open access: yesFrontiers in Oncology
The malignant mesothelioma mainly develops in the pleura and peritoneum, while primary ovarian mesothelioma is very rare. Here, we report the first case of primary ovarian mesothelioma (clear cell variant) with VHL mutations in the world based on the ...
Ye Yao, Hao Yan, Jing Xiong, Yaqi Duan
doaj   +1 more source

An electron microscopic study of a solitary pleural mesothelioma [PDF]

open access: bronze, 1964
Sarah A. Luse, Harlan J. Spjut
openalex   +1 more source

A Machine Learning‐Optimized Immunogenic Cell Death Signature Reveals Tumor Immunogenicity and the Immunotherapy Response of Pancancer

open access: yesMedComm – Future Medicine, Volume 4, Issue 4, December 2025.
This study introduces an innovative adversarial validation (AV) strategy integrated with machine learning to mitigate the problem of data set shift and enhance analyses of pan‐cancer immunogenicity. It identifies key immunogenic cell death‐related biomarkers and demonstrates their predictive potential for survival outcomes and responses to PD‐1 ...
Li Qiu   +22 more
wiley   +1 more source

Hippo pathway effectors are associated with glioma patient survival, control cell proliferation and sterol metabolism through TEAD3

open access: yesBrain Pathology, Volume 35, Issue 6, November 2025.
The Hippo pathway transcription factor TEAD3 represents an independent prognostic biomarker of tumor recurrence and a potential therapeutic vulnerability through its regulation of cholesterol metabolism in glioma. Abstract Glioblastomas represent the most common and lethal primary brain tumors in the world.
Konstantin Masliantsev   +10 more
wiley   +1 more source

Exposure to Asbestos and Mesothelioma of the Pleura [PDF]

open access: bronze, 1964
P.B.S. Fowler   +2 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, Volume 19, Issue 10, Page 2833-2859, October 2025.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Comprehensive Insights into Tracheoesophageal Fistula Pathophysiology, Diagnosis, Treatment, and Future Directions

open access: yesAdvanced Science, Volume 12, Issue 37, October 6, 2025.
Tracheoesophageal fistula (TEF), a pathological trachea‐esophagus connection, arises congenitally or from malignancy/radiotherapy/trauma, causing aspiration and malnutrition. Diagnosis utilizes imaging and endoscopy. Treatment ranges from endoscopic stenting to surgical repair and conservative management.
Gang Li   +10 more
wiley   +1 more source

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