Results 141 to 150 of about 136,561 (344)

Estimation of the global burden of mesothelioma deaths from incomplete national mortality data

Occupational and Environmental Medicine, 2017
Background Mesothelioma is increasingly recognised as a global health issue and the assessment of its global burden is warranted. Objectives To descriptively analyse national mortality data and to use reported and estimated data to calculate the global ...
Chimed-Ochir Odgerel, Ken Takahashi, T. Sorahan, T. Driscoll, C. Fitzmaurice, M. Yokoo, K. Sawanyawisuth, Sugio Furuya, F. Tanaka, S. Horie, N. van Zandwijk, J. Takala   +11 more
semanticscholar   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Pediatric patient with peritoneal mesothelioma harboring ALK rearrangement

Current Problems in Cancer: Case Reports, 2021
Malignant mesothelioma is a rare disease that typically occurs in older patients with prolonged exposure to asbestos. The majority of mesothelioma occurs in the pleura.
Reema A Patel, MD, Miranda Lin, BS, Megan M Harper, MS, MD, Sandra J Beck, MD, Charles S Dietrich, MD, Jill M Kolesar, PhD, MS, Susanne M Arnold, MD, John Hahn, MD, Prakash K Pandalai, MD, Shadi A Qasem, MD, Joseph Kim, MD   +10 more
doaj  

Environmental asbestos exposure and risk of mesothelioma.

Annals of Translational Medicine, 2017
Mesothelioma is commonly considered an occupational disease occurring as a result of asbestos exposure in the workplace. Several avenues for environmental asbestos exposures have been described and may be associated with asbestos related disease ...
C. Noonan
semanticscholar   +1 more source

KEYNOTE‐A17: First‐Line Pembrolizumab Plus Cisplatin–Pemetrexed in Japanese Participants With Advanced Pleural Mesothelioma

Cancer Science, EarlyView.
In the phase 1b KEYNOTE‐A17 study of first‐line pembrolizumab plus chemotherapy in Japanese participants with advanced pleural mesothelioma (PM), 2 of 18 participants (11%) evaluated experienced dose‐limiting toxicities. The objective response rate among all 19 participants in the study was 74%, with 14 participants achieving a partial response and a ...
Takashi Kijima, Terufumi Kato, Yasushi Goto, Kozo Kuribayashi, Koji Mikami, Yoshiki Negi, Shuji Murakami, Tatsuya Yoshida, Masae Homma, Akira Wakana, Kazuo Noguchi, Nobukazu Fujimoto   +11 more
wiley   +1 more source

Antitumor Activities by a Humanized Cancer‐Specific Anti‐Podoplanin Monoclonal Antibody humPMab‐117 Against Human Tumors

Cancer Science, EarlyView.
A humanized cancer‐specific anti‐podoplanin monoclonal antibody humPMab‐117 exerts antibody‐dependent cellular cytotoxicity and complement‐dependent cytotoxicity against human tumor cells. In the xenograft tumor models, humPMab‐117 demonstrated strong antitumor efficacy.
Tomohiro Tanaka, Hiroyuki Suzuki, Tomokazu Ohishi, Manabu Kawada, Mika K. Kaneko, Yukinari Kato   +5 more
wiley   +1 more source

PBK Expression Promotes the Aggressive Phenotypes of Mesothelioma

Cancer Science, EarlyView.
PBK plays a crucial role in cell survival in mesothelioma and is associated with worse outcome. PBK is a promising therapeutic target that may serve as a prognostic biomarker, enabling personalized treatment of mesothelioma. ABSTRACT Mesothelioma is one of the most aggressive neoplasms worldwide that has a particularly poor prognosis.
Kazumi Hori, Ichidai Tanaka, Tatsuhiro Sato, Mika Sato, Yuta Kodama, Hideyuki Itoigawa, Yuichi Abe, Taketo Kato, Ayumu Taguchi, Mitsuo Sato, Yoshitaka Sekido, Toyofumi Fengshi Chen‐Yoshikawa, Makoto Ishii   +12 more
wiley   +1 more source

Mesothelioma [PDF]

Annals of Oncology, 2010
openaire   +4 more sources

MONITORING OF MESOTHELIOMA IN SOUTHERN BRAZIL: A SITUATION TO BE INVESTIGATED

Cogitare Enfermagem, 2017
Brazil is one of the world’s greatest producers of chrysotile, but the occurrence of mesothelioma is apparently low. However, identification of cases of mesothelioma is difficult due to errors of diagnosis and registries of deaths.
Francisco José Koller, Leila Maria Mansano Sarquis, Maria de Fátima Mantovani, Fernanda Moura D’Almeida Miranda, Dario Consonni, Carolina Mensi   +5 more
doaj   +1 more source

Epigenetically‐Upregulated CD98 Shed Light on the Precancerous Diagnosis and Prognosis Prediction of Esophageal Cancer

Cancer Science, EarlyView.
This study confirmed that hypomethylation‐induced upregulation of CD98 promoted ESCC cell proliferation by regulating the cell cycle and was correlated with poorer overall survival of ESCC patients. Combined panels of immunohistochemistry (CD98 and P53) are recommended for accurate diagnosis of esophageal precancerous lesions.
Xue Zhang, Mengfei Sun, Na Li, Jie Yu, Wenjie Wang, Ju Yang, Hongyan Wu, Linyue Zhao, Huakun Zhang, Lan Yang, Feng Li, Qi Sun, Yunzhao Chen, Xiaobin Cui   +13 more
wiley   +1 more source