Results 41 to 50 of about 9,607 (255)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

A low complexity detection algorithm for large scale multiuser MIMO based on message passing

open access: yesDianxin kexue, 2017
According to the problem of high complexity of base station detection in large scale multiuser multiple input multiple output (MIMO) system,a low complexity multiuser variable node full information Gaussian message passing iterative detection algorithm ...
Qiong WANG, Wei YE, Mingming JI
doaj   +2 more sources

Resource allocation in NOMA heterogeneous network based on MEC

open access: yesTongxin xuebao, 2020
Aiming at maximizing the cache revenue,a joint user association and power allocation algorithm was proposed for the matching of base stations with users and power allocation in a NOMA heterogeneous network with caches,a NOMA joint optimization algorithm ...
Haijun ZHANG, Zizheng ZHANG, Keping LONG
doaj   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Sphere‐decoding based equalization for reduced‐zero‐padding orthogonal time frequency space modulation

open access: yesIET Communications, 2023
This work studies the equalization methods for the reduced zero‐padding version of the orthogonal time frequency space modulation. Here, the focus is on applications in low data rate scenarios such as the Internet of Things, and the case where the number
Yuan Zhang, Peng Du
doaj   +1 more source

Expander graph arguments for message-passing algorithms [PDF]

open access: yesIEEE Transactions on Information Theory, 2001
Summary: We show how expander-based arguments may be used to prove that message-passing algorithms can correct a linear number of erroneous messages. The implication of this result is that when the block length is sufficiently large, once a message-passing algorithm has corrected a sufficiently large fraction of the errors, it will eventually correct ...
David Burshtein, Gadi Miller
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

A Semi-Analytic Algorithm to Estimate Clusters With Loops in Percolation on Real Networks

open access: yesIEEE Access
Estimating the percolating cluster fraction is central to many percolation models. For real networks, the total size of clusters with loops can be considered a plausible metric for this fraction.
Chenguang Li, Tao Fu, Lian Wang, Ran Sun
doaj   +1 more source

Learned Turbo Message Passing for Affine Rank Minimization and Compressed Robust Principal Component Analysis

open access: yesIEEE Access, 2019
This paper is focused on the efficient algorithm design for affine rank minimization (ARM) and compressed robust principal component analysis (CRPCA). Given the proliferation of the literature on the ARM and CRPCA problems, the existing algorithms mostly
Xuehai He, Zhipeng Xue, Xiaojun Yuan
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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