Results 21 to 30 of about 7,368 (120)

Carcinomatous encephalitis as clinical presentation of occult lung adenocarcinoma: case report Encefalite carcinomatosa como apresentação inicial de adenocarcinoma de pulmão oculto: relato de caso

Arquivos de Neuro-Psiquiatria, 2007
Carcinomatous encephalitis is a rare entity, originally described by Madow and Alpers in 1951, which is characterized by tumoral spreading perivascular, without mass effect.
Henrique Barbosa Ribeiro, Tadeu Ferreira de Paiva Jr, Gustavo Pignatari Rosas Mamprin, Milton Luiz Gorzoni, Antônio José da Rocha, Carmen Lucia Penteado Lancellotti   +5 more
doaj   +1 more source

Metástase de carcinoma de mama na hipofise: relato de um caso

Arquivos de Neuro-Psiquiatria, 1978
É relatado o caso de paciente feminina de 65 anos de idade que apresentou sintomatologia neurológica com evolução de um mês, com progressão rápida para a morte.
Ligia Maria Barbosa Coutinho, Roque Furian   +1 more
doaj   +1 more source

Metastase cerebral como forma de apresentação de carcinoma basalóide do esófago.

Acta Médica Portuguesa, 1995
A case of oesophageal basaloid carcinoma is reported. The disease was revealed as a brain metastasis and was found ad initium to be in an advanced stage, with evidence of brain, lung and liver metastasis.
I R Carvalho, R M Lima, A Serafim, M M Lemos, J Cristas, J Machado, H Oliveira   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, Volume 20, Issue 9, Page 2220-2242, September 2026.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Tehnik Proteksi Otak pada Pembedahan Non Neurosurgery (Radical Neck Dissection) dengan Premorbid Space Occupying Lesion (SOL) dan Infark Serebri

Jurnal Neuroanestesi Indonesia, 2014
Insidensi kasus tumor dengan metastase otak berkisar antara 100.000 sampai 170.000 pertahun. Metastase otak bersifat multiple dengan 80% terletak pada hemis ferserebri.
Buyung Hartiyo Laksono, Siti Chasnak Saleh   +1 more
doaj   +1 more source

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, Volume 19, Issue 11, Page 3023-3034, November 2025.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Brain metastasis of hepatocellular carcinoma detected after liver transplantation Metástase cerebral de carcinoma hepatocelular após transplante de fígado

Arquivos de Gastroenterologia, 2004
AIM: We report the case of a patient with hepatocellular carcinoma submitted to liver transplantation, who subsequently manifested tumor recurrence initially as brain metastasis.
Alex Vianey Callado França, Ana Martinelli, Orlando Castro e Silva Jr.   +2 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, Volume 19, Issue 10, Page 2833-2859, October 2025.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Coriocarcinoma Metastático. Relato de caso

Revista de Saúde, 2017
O processo de fecundação de um óvulo e o desenvolvimento da gravidez é um processo complexo que é suscetível a diversas falhas, dentre elas as doenças trofoblásticas gestacionais, que podem ainda evoluir para neoplasias trofoblásticas gestacionais ...
Felipe Maciel Pereira, Maria Cristina Almeida de Souza, Carolina de Paula Orioli, Edsneider Rocha Pires de Souza, João Carlos de Souza Côrtes Júnior, Rodrigo dos Santos Maganha   +5 more
doaj   +1 more source

Real‐world management bei Patienten mit Komplettremission unter Immuncheckpoint‐Inhibition bei fortgeschrittenem Melanom

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 3, Page 321-329, March 2025.
Zusammenfassung Hintergrund Bislang wurde die optimale Behandlungsdauer mit Immuncheckpoint‐Inhibitoren (ICI) noch nicht in prospektiven Studien untersucht. In der Routineversorgung muss jedoch immer wieder eine Entscheidung über die Behandlungsdauer bei Patienten mit Komplettremission unter ICI getroffen werden.
Markus Reitmajer, Elisabeth Livingstone, Kai‐Martin Thoms, Markus V. Heppt, Frank Meiss, Anja Gesierich, Konstantin Drexler, Lucie Heinzerling, Friedegund Meier, Christian Menzer, Max Schlaak, Lisa Zimmer, Andrea Forschner   +12 more
wiley   +1 more source