Results 61 to 70 of about 413,432 (237)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Avanços no tratamento cirúrgico das metástases hepáticas colorretais

, 2011
ResumoO câncer colorretal é o terceiro tumor mais frequente no ocidente. Cerca de 50% dos pacientes desenvolvem metástases hepáticas na evolução da doença, as quais são responsáveis por, no mínimo, dois terços das mortes1-6.
Felipe José Fernández Coimbra, Pires, Thiago Costa, Diniz, Alessandro Landskron, Junior, Wilson Luiz da Costa, Héber Salvador de Castro Ribeiro, Ribeiro, Héber Salvador de Castro, Alessandro Landskron Diniz, Thiago Costa Pires, Coimbra, Felipe José Fernández, Wilson Luiz da Costa Junior   +9 more
core   +1 more source

F FDG PET-CT Metástases em tecidos moles de câncer de tireoide diagnosticadas por 18 F FDG PET-CT [PDF]

, 2020
SUMMARY Distant metastases of differentiated thyroid cancer are unusual; lung and bones are the most frequently affected sites. Soft tissue metastases (STM) are extremely rare.
Martín Coduti, Sergio Quildrian, Leonardo Califano, Inés Califano, José Otero, Erica Rojas Bilbao   +5 more
core  

Carcinoma de células escamosas da língua e metástases renais bilaterais

, 2021
Squamous cell carcinoma of the tongue is the most common malignant tumor of the oral cavity. The finding of metastases, in this type of cancer, is considered the main factor of poor prognosis with a marked effect on the overall survival.
Boccalatte, Luis, Larrañaga, Juan, Bruballa, Rocio, Abuawad, Carla   +3 more
core   +1 more source

Adenocarcinoma pulmonar em um bovino Pulmonary adenocarcinoma in a bovine

Ciência Rural, 2010
Um bovino Guzerá, fêmea, adulto, com histórico de insuficiência cardíaca congestiva direita de duração de duas semanas, morreu durante o transporte ao hospital veterinário.
Aline de Marco Viott, Ingeborg Maria Langohr, Fábio Augusto Vannucci, Aliny Pontes Almeida, Rômulo Cerqueira Leite, Roselene Ecco   +5 more
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Metástases hepáticas de primário difícil de encontrar…

Galicia Clínica, 2017
Metastatic Cancer of Unknown Primary Site (CUP) accounts for approximately 3-5% of all malignant neoplasms and is therefore one of the 10 most frequent cancer diagnoses in men.
Ana Mondragão, Silvia Costa, Marta Barbedo, Vitor Paixão Dias   +3 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Metástases Suprarrenais

, 2015
A crescente disponibilidade e definição dos exames complementares de diagnóstico, nomeadamente imagiológico, tem levado ao aumento do número de nódulos suprarrenais detetados.
Serra, Carlos
core  

Metástases esplénicas no adenocarcinoma seroso do ovário.

Acta Médica Portuguesa, 2008
Splenic metastasis is rare, and is usually associated with disseminated malignancy. The primary tumours more frequently related with splenic metastasis are lung, breast, gynaecologic, specially ovary tumours, colon, rectum and melanoma.
Rita Roque, António Pina, Carmo Soares, António Martinho, Humberto Messias   +4 more
doaj   +1 more source