Results 171 to 180 of about 4,403,667 (297)

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

Who defines the question in neglected tropical disease research? [PDF]

open access: yesPLoS Negl Trop Dis
Francisco AM   +4 more
europepmc   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

7183 Outcomes in metastatic (met) germ cell tumours (GCT): 5-year experience from a single institution

open access: yesEuropean Journal of Cancer Supplements, 2009
M.P. Decatris, P. Kitsios, A. Horwich
openaire   +1 more source

Production upgrading and skills development in the Western Cape clothing sector: are industry requirements being met by institutional policy implications?

open access: yes, 2016
This research paper presents an overview and analysis of skills development in the Western Cape clothing sector in the context of production upgrading. The analysis touches on the broader South African skills development framework and industrial policy towards the clothing sector, notably the shift from mass production towards the adoption of Lean ...
openaire   +1 more source

Disease, Institutions and Underdevelopment [PDF]

open access: yes
What explains poverty of Sub Saharan Africa and South Asia? One view holds the disease environment of these regions as the primary culprit. Others see it as a typical symptom of growth retarding institutions.
Hasan, Lubna
core  

Metformin Ameliorates Diabetes-Associated Cognitive Dysfunction via p53/Parkin-Mediated Mitophagy. [PDF]

open access: yesDiabetes Obes Metab
Xu W   +11 more
europepmc   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Australia's HECS Policy: Fewer Social, but more Political Barriers [PDF]

open access: yes
This paper is one of a series that has empirically tested the proposition that whilst the Higher Education Contribution Scheme (HECS) was implemented with the intention of improving access to university education for all Australians, it has had ...
Braithwaite, Valerie   +2 more
core  

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