Results 241 to 250 of about 256,459 (268)

On Determination Method for Resolution of Secondary Electron Images in Scanning Electron Microscopy

Advanced Science, EarlyView.
An idealized SEM, termed Rayleigh's microscope, is constructed by Monte Carlo simulation to represent imaging conditions that just satisfy the Rayleigh criterion. Based on this physically defined model, sharpness–resolution conversion curves are established and combined with the Rose criterion, enabling automated resolution evaluation from practical ...
Tongfang Yang, Yanbo Zou, Zejun Ding
wiley   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

From diabetes to dentistry: metformin targets mitochondrial-immune crosstalk to restore periodontal homeostasis. [PDF]

J Transl Med
Wu M, Wang F, Zhang Y, Xing A, Li Z, Lu X, Lai Y, Zhao B, Sun B.   +8 more
europepmc   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Prognostic Value of Murray's Law-Based Quantitative Flow Ratio in Multi-Arterial Coronary Artery Bypass Grafting. [PDF]

JACC Asia
Qi Z, Zhu J, Qin K, Wang Z, Ye X, Zhou M, Li H, Qiu J, Xu H, Sun Y, Zhang W, Zhu Y, Zhao Q.   +12 more
europepmc   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

Advanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao, Xin Wang, Jing Zhang, Ryan McQuinn, Je Min Lee, Itay Gonda, Ari Feder, Yimin Xu, Baike Wang, Qinghui Yu, Denise M. Tieman, Sanwen Huang, Harry Klee, James J. Giovannoni, Zhangjun Fei   +14 more
wiley   +1 more source

HIF-1α Promotes Macrophage Extracellular Trap Formation and Exacerbates Acute Lung Injury in Neonatal Sepsis. [PDF]

Biomedicines
Zhang H, Huang W, Dai X, Zheng J, Jiang X, Yang Y, Zhong H, Yang G.   +7 more
europepmc   +1 more source

Muscle energy techniques for post-stroke spasticity: mechanisms and clinical applications. [PDF]

Front Neurol
Qian L, Shi Y, Liu W, Yao Q.
europepmc   +1 more source

The Phoenix Criteria and Other Severity Scores in Identifying Pediatric Sepsis.

JAMA Netw Open
He S, Zhang JZ, Chan LC, Lin A, Yeung KY, Kuok MCI, Cheng JWCH, Au DCY, Chow CY, Wong TW, Wong WK, Chan E, Young HM, Wong EM, Ho KM, Lee A, Rhee C, Lam HS, Ling L.   +18 more
europepmc   +1 more source

Elevated TMEM45B expression promotes liver cancer progression and is associated with MET signaling activation. [PDF]

Sci Rep
Shen H, Zheng W, Li M, Pei L, Xie J.
europepmc   +1 more source